The retrospective evaluation of pneumonia and bronchitis cases in infants and small children with atopic dermatitis in the practice of a family doctor - personal observations.

PURPOSE: The purpose of the work is to estimate the occurrence of lower respiratory tract infections in infants and small children with atopic dermatitis and to compare them with a group of children at the same age without features of allergy. MATERIAL AND METHODS: The study has been conducted on the basis of the retrospective analysis of medical documentation of individual history of disease among children born in 2005 - 2008 treated in an outpatient clinic. RESULTS: Children suffering from atopic dermatitis are more prone to pneumonia and bronchitis. They are also more often hospitalized due to these reasons. Also, this group of patients is more liable to wheezing in the time of infection. CONCLUSIONS: Infants and small children with atopic dermatitis are more prone to lower respiratory tract infections. Recurrence of infections within the respiratory system may be an important risk factor for asthma.

[Retinoids in the treatment of skin diseases in the light of the data of the Dermatology Clinic, Medical Academy, in Lódz]. / Retinoidy w leczeniu chorób skóry w swietle materialu Kliniki Dermatologicznej WAM w Lodzi.

Tigason was applied in 51 patients with psoriasis and 19 with other skin diseases. In 18 patients was applied alone, in 42 combined with PUVA and in 10 with SUP. Roaccutan was applied in 18 patients with acne conglobata et phlegmonous resistant to other methods of treatment. Tigason was found to be a useful drug in psoriasis and some other skin diseases. The combination with PUVA or SUP allowed to reduce the doses of drugs and the dose of radiation. Roaccutan was found to be a useful drug in severe forms of acne vulgaris. The side effects of the treatment with retinoids were transient and they did not create danger to the patients.

[Leukocyte migration test following stimulation with protein factor of neutrophilic granulocytes (PMNL) in the peripheral blood of patients with psoriasis]. / Leukozytenmigrationstest nach Stimulation mit Proteinfaktor aus neutrophilen Granulozyten (PMNL) des peripheren Blutes bei Psoriasiskranken.

Blood investigations were performed in 43 patients suffering from generalized psoriasis vulgaris and 40 healthy test persons. The results were statistically evaluated with the help of the computer technique. In the patients with active psoriasis, we found stimulation of the leucocyte migration caused by the autogenic protein factor from the peripheral blood PMNL. In addition, we observed that a mechanism like this may occur in vivo under the influence of biological degranulation factors (bacterial antigens from intraorganic infection foci). The mechanism described ist likely to act in an autoimmunostimulating way on immunologic reactions and is one of the elements which stimulate the PMNL activity in psoriatics. These results support our opinion that psoriasis is a systemic disease and indicate the role of the PMNL protein factor regarding the development of the psoriatic reaction.