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Klin Med (Mosk) ; 85(1): 31-5, 2007.
Article in Russian | MEDLINE | ID: mdl-17419352

ABSTRACT

The influence of "space weather" (effects of geomagnetic and meteorological activity) on the effectiveness of antihypertensive therapy in patients with arterial hypertension was studied. Blood pressure monitoring using self-control technology was conducted during 12 weeks in 33 patients with I to II degree arterial hypertension receiving different antihypertensive agents in Myasnikov Cardiology Research Institute. Two groups of patients were distinguished according to the effectiveness of the therapy; groups of patients who had two- to four-week periods of spontaneous rhythmical variations of arterial pressure and/or an eluding hypotensive effect, were found as well. Matching these data to the data on geomagnetic activity as well as atmospheric pressure and temperature revealed magnetosensitive patients in the group with multipronged structural and functional changes in target organs requiring combined therapy. The effects of spontaneous rhythmical variations in blood pressure and the effects of antihypertensive therapy elusion, including those in the group of easier-to-treat patients, also correlated with geomagnetic and meteorological activity. These pilot studies demonstrated the necessity to take space weather effects into account when examining and treating cardiological patients, as well as the fact that further research in this direction is needed to clarify what algorithms will be necessary for this purpose.


Subject(s)
Blood Pressure/physiology , Circadian Rhythm/physiology , Hypertension/physiopathology , Magnetics/adverse effects , Weather , Blood Pressure Monitoring, Ambulatory , Disease Progression , Follow-Up Studies , Humans , Male , Middle Aged , Prognosis , Retrospective Studies
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