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1.
Saudi J Gastroenterol ; 22(1): 43-9, 2016.
Article in English | MEDLINE | ID: mdl-26831606

ABSTRACT

BACKGROUND/AIMS: Optical colonoscopy (OC) is the primary modality for investigation of colonic pathology. Although there is data on demographic factors for incomplete OC, paucity of data exists for anatomic variables that are associated with an incomplete OC. These anatomic variables can be visualized using computed tomographic colonography (CTC). We aim to retrospectively identify variables associated with incomplete OC using CTC and develop a scoring method to predict the outcome of OC. PATIENTS AND METHODS: In this case-control study, 70 cases ( with incomplete OC) and 70 controls (with complete OC) were identified. CTC images of cases and controls were independently reviewed by a single CTC radiologist. Demographic and anatomical parameters were recorded. Data was examined using descriptive linear statistics and multivariate logistic regression model. RESULTS: On analysis, female gender (80% vs 58.6% P = 0.007), prior abdominal/pelvic surgeries (51.4% vs 14.3% P < 0.001), colonic length (187.6 ± 30.0 cm vs 163.8 ± 27.2 cm P < 0.001), and number of flexures (11.4 ± 3.1 vs 8.4 ± 2.9 P < 0.001) increased the risk for incomplete OC. No significant association was observed for increasing age (P = 0.881) and history of severe diverticulosis (P = 0.867) with incomplete OC. A scoring system to predict the outcome of OC is proposed based on CTC findings. CONCLUSION: Female gender, prior surgery, and increasing colonic length and tortuosity were associated with incomplete OC, whereas increasing age and history of severe diverticulosis were not. These factors may be used in the future to predict those patients who are at risk of incomplete OC.


Subject(s)
Colonic Diseases/diagnostic imaging , Colonography, Computed Tomographic/methods , Aged , Case-Control Studies , Colonic Diseases/pathology , Female , Humans , Male , Middle Aged , Retrospective Studies , Risk Factors
2.
Abdom Imaging ; 40(5): 1121-30, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25504375

ABSTRACT

PURPOSE: The purpose of the study is to evaluate the CT appearance and pattern of metastatic disease of patients with surgically resected well-differentiated duodenal neuroendocrine tumors who underwent pre-operative dual-phase CT. METHODS: Clinical and pathologic records and CT images of 28 patients (average age 58.0 years) following Whipple procedure were retrospectively reviewed. The size, morphology (polypoid, intraluminal mass or wall thickening, intramural mass), location, CT attenuation in the arterial and venous phases, and the presence of lymph node or liver metastases were recorded. RESULTS: On CT, 19 patients (67.8%) had neuroendocrine tumors manifested as polypoid or intraluminal masses (38 lesions, multiple tumors in 3 patients), 4 patients (14.3%) had tumors manifested as wall thickening or intramural masses, and in 5 patients (17.9%), the primary tumor was not visualized. Lesions not seen at CT were less than 0.8 cm on pathologic diagnosis. The mean size of polypoid tumors on CT was 1.2 cm (range 0.3-3.8 cm); 24 tumors were 1.0 cm or smaller, and 14 tumors were larger than 1.0 cm. Most lesions were hypervascular in the arterial phase (19/23 patients) with an increase in tumor enhancement in the venous phase in 14 patients (60.9%), decrease in enhancement in 7 patients (30.4%), and no change in enhancement in 2 patients (8.7%). Thirteen patients (46.4%) had metastatic disease from carcinoid tumor, most commonly regional enhancing lymphadenopathy. CONCLUSION: Duodenal carcinoid tumors commonly appear as an enhancing mass in either the arterial or venous phases. If a primary tumor is not seen in the duodenum, adjacent enhancing lymphadenopathy can be a clue to the presence of a duodenal carcinoid tumor.


Subject(s)
Duodenal Neoplasms/diagnostic imaging , Duodenal Neoplasms/pathology , Liver Neoplasms/diagnostic imaging , Neoplasms, Second Primary/diagnostic imaging , Neuroendocrine Tumors/diagnostic imaging , Neuroendocrine Tumors/pathology , Tomography, X-Ray Computed , Adult , Aged , Contrast Media , Duodenum/pathology , Female , Humans , Liver/diagnostic imaging , Liver Neoplasms/secondary , Lymphatic Metastasis , Male , Middle Aged , Multidetector Computed Tomography , Retrospective Studies
3.
J Comput Assist Tomogr ; 38(1): 146-52, 2014.
Article in English | MEDLINE | ID: mdl-24424563

ABSTRACT

OBJECTIVE: This article aimed to study features on dual-phase computed tomography (CT) that help differentiate autoimmune pancreatitis (AIP) from pancreatic adenocarcinoma (PA). METHODS: The CTs of 32 patients with AIP were matched with equal number of PA and were independently evaluated by 3 radiologists who assigned a diagnosis of AIP, PA, or unsure. Interobserver agreement between radiologists was evaluated using κ statistics. RESULTS: The mean accuracies for diagnosing AIP and PA were 68% and 83%, respectively. There was moderate agreement between radiologists (κ, 0.58; P < 0.0001). The most common findings for AIP were common bile duct (CBD) stricture (63%), bile duct wall hyperenhancement (47%), and diffuse parenchymal enlargement (41%). The most common findings for PA were focal mass (78%; κ, 0.58; P < 0.0001) and pancreatic ductal dilatation (69%; κ, 0.7; P < 0.0001). Findings helpful for diagnosing AIP were diffuse enlargement, parenchymal atrophy as well as absence of pancreatic duct dilatation and focal mass. Findings helpful for diagnosing PA were focal mass and pancreatic ductal dilatation. Misdiagnosis of PA in patients with AIP was due to focal mass, pancreatic duct dilatation, and pancreatic atrophy, whereas misdiagnosis of AIP in patients with PA was due to absence of atrophy, presence of diffuse enlargement, and peripancreatic halo. CONCLUSIONS: Diffuse enlargement, hypoenhancement, and characteristic peripancreatic halo are strong indicators for a diagnosis of AIP. Radiologists demonstrated moderate agreement in distinguishing AIP from PA on the basis of CT imaging.


Subject(s)
Adenocarcinoma/diagnostic imaging , Autoimmune Diseases/diagnostic imaging , Pancreatic Neoplasms/diagnostic imaging , Pancreatitis/diagnostic imaging , Tomography, X-Ray Computed/methods , Adenocarcinoma/pathology , Adult , Aged , Aged, 80 and over , Autoimmune Diseases/pathology , Contrast Media , Diagnosis, Differential , Female , Humans , Iohexol , Male , Middle Aged , Pancreatic Neoplasms/pathology , Pancreatitis/pathology , Retrospective Studies
4.
J Radiol Case Rep ; 7(11): 32-7, 2013 Nov.
Article in English | MEDLINE | ID: mdl-24421928

ABSTRACT

Duodenal duplication cysts are a rare subtype of gastrointestinal duplications cysts. Approximately 5% of gastrointestinal duplication cysts occur in the duodenum. An 18-year-old woman presented with epigastric pain and a subjective abdominal bulge. A computed tomography scan was subsequently performed and showed a solid and cystic mass with wall calcifications in the lesser sac of the upper abdomen. A duodenal duplication cyst was found unexpectedly on histopathologic analysis. This was also an unusual case as there was no evidence of malignancy. Four years after surgery, the patient remains asymptomatic. We present a brief literature review on duodenal duplication cysts and discuss its differential diagnosis.


Subject(s)
Cysts/pathology , Duodenal Diseases/pathology , Duodenum/abnormalities , Abdominal Pain/etiology , Adolescent , Calcinosis/diagnostic imaging , Calcinosis/pathology , Calcinosis/surgery , Cysts/diagnostic imaging , Cysts/surgery , Duodenal Diseases/diagnostic imaging , Duodenal Diseases/surgery , Female , Humans , Incidental Findings , Radiography
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