ABSTRACT
A 29-year-old male patient suffered from paraplegia 6 months after brain injury. Heterotopic ossification was diagnosed based on clinical characteristics such as decreased range of motion at the bilateral hips without infective signs. A planar bone scintigraphy using Tc-MDP showed intensive radiotracer accumulation in the proximal portion of the bilateral femurs and the right acetabulum. The SPECT/CT images showed increased radiotracer accumulation in the adjacent soft tissues of the bilateral hips but not in the bone. The conservative treatment rather than surgical intervention was given according to the findings in bone SPECT/CT images.
Subject(s)
Bones of Lower Extremity/diagnostic imaging , Image Interpretation, Computer-Assisted , Ossification, Heterotopic/diagnostic imaging , Tomography, Emission-Computed, Single-Photon , Tomography, X-Ray Computed , Adult , Humans , Male , Multimodal ImagingABSTRACT
A 53-year-old woman with a history of nasopharyngeal carcinoma underwent (99m)Tc methylene diphosphonate (MDP) whole-body scintigraphy for tumor staging. An MDP-avid lesion located in the urinary bladder was found. Computed tomography showed a protruding mass with calcific surface in the left inferolateral wall of the urinary bladder. A biopsy was conducted and the pathological report confirmed the diagnosis of transitional cell carcinoma. The patient received transurethral resection and Bacillus Calmette-Guérin intravesical therapy. Four months later, she underwent an (18)F-FDG PET/CT scan. Unfortunately, tumor recurrence in the bladder cancer was diagnosed by the (18)F-FDG PET/CT scan.
Subject(s)
Bone and Bones/diagnostic imaging , Incidental Findings , Technetium Tc 99m Medronate , Urinary Bladder Neoplasms/diagnostic imaging , Whole Body Imaging , Female , Humans , Middle Aged , Multimodal Imaging , Positron-Emission Tomography , Tomography, X-Ray Computed , Urinary Bladder Neoplasms/therapyABSTRACT
OBJECTIVE: Neuroendocrine cervical carcinoma is a rare subtype of cervical cancer. These tumors exhibit an aggressive behavior with early regional lymph node and distant metastases. The purpose of our study was to describe five cases of neuroendocrine cervical-vaginal carcinoma and to discuss the potential of the 2-[(18)F] fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) scan for the detection of this rare malignancy. MATERIALS AND METHODS: Five cases of cervical-vaginal neuroendocrine tumor were retrospectively collected, during a two year (from September 2009 to August 2011) period in our hospital. The clinical staging distributions were International Federation of Gynecology and Obstetrics (FIGO) stage IB2 (1 of 5), stage IIA (3 of 5) and stage IVA (1 of 5). RESULTS: Two cases (cases 1 and 4) were restaged after (18)F-FDG PET/CT scan in the initial staging process. Post-treatment (18)F-FDG PET/CT scans, in three patients, revealed positive findings for tumor recurrence or lymph node metastases. Two patients (cases 2 and 3) died of tumor within two years. CONCLUSION: (18)F-FDG PET/CT scan is a useful tool in cervical-vaginal neuroendocrine tumor. In its initial staging, the (18)F-FDG PET/CT scan may help assess the possible nodal involvement or early hematogeneous spreading. We can also use the (18)F-FDG PET/CT to detect local recurrence and to evaluate the treatment response after clinical manipulation.
Subject(s)
Carcinoma, Neuroendocrine/diagnostic imaging , Fluorodeoxyglucose F18 , Radiopharmaceuticals , Uterine Cervical Neoplasms/diagnostic imaging , Vaginal Neoplasms/diagnostic imaging , Adult , Aged , Carcinoma, Neuroendocrine/pathology , Carcinoma, Neuroendocrine/therapy , Female , Humans , Middle Aged , Radionuclide Imaging , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/therapy , Vaginal Neoplasms/pathology , Vaginal Neoplasms/therapyABSTRACT
The present study was to characterize turkey coronavirus associated with turkey poult enteritis and mortality. Intestinal contents or intestines from affected turkey poults and inoculated turkey embryos contained coronaviruses as revealed by electron microscopy or were positive for turkey coronavirus by immunofluorescent antibody assay. Sucrose density gradient ultracentrifugation of the virus-containing intestinal homogenate yielded two opalescent bands corresponding to the buoyant densities of 1.14-1.15 and 1.18-1.20 g/ml, respectively. Coronaviral particles from intestinal contents or the sucrose density gradient preparation were mainly spherical in shape and had envelope and central depression. They were surrounded by a fringe of regularly spaced petal-shaped projections attached to the particles by a short stalk. Purified viruses hemagglutinated rabbit erythrocytes with a titer of 16. Major protein bands of purified viruses analyzed by SDS-PAGE were located at 200, 100-110, 50-60, and 30-35 kDa. The patterns of protein bands were consistent with those of Minnesota or Quebec turkey coronavirus isolates. A 568 bp nucleotide fragment of turkey coronavirus spike protein gene was amplified from RNA of inoculated turkey embryo intestine or purified virus. Sequence analysis of the 568 bp PCR product revealed high degree of identity with the corresponding spike protein gene sequence of human and bovine coronaviruses. The results indicated that turkey coronavirus was associated with turkey poults with acute enteritis.
