ABSTRACT
Using knowledge gained from bioengineering studies, current vascular research focuses on the delineation of the natural history and risk assessment of clinical vascular entities with significant morbidity and mortality, making the development of new, more accurate predictive criteria a great challenge. Additionally, conclusions derived from computational simulation studies have enabled the improvement and modification of many biotechnology products that are used routinely in the treatment of vascular diseases. This review highlights the promising role of the bioengineering applications in the vascular field.
Subject(s)
Bioengineering , Biomedical Research/methods , Blood Vessels , Computer Simulation , Models, Cardiovascular , Vascular Diseases , Animals , Biomechanical Phenomena , Blood Vessel Prosthesis Implantation , Blood Vessels/pathology , Blood Vessels/physiopathology , Endovascular Procedures , Hemodynamics , Humans , Prognosis , Risk Assessment , Risk Factors , Vascular Diseases/diagnosis , Vascular Diseases/pathology , Vascular Diseases/physiopathology , Vascular Diseases/therapyABSTRACT
Upper limb vein aneurysms complicate all types of autogenous arteriovenous fistulae (AVF) and comprise false aneurysms secondary to venipuncture trauma as well as true aneurysms, characterized by dilatation of native veins. The dilatation of a normal vein and the development of a true aneurysm are strongly influenced by local hemodynamic factors affecting the flow in the drainage venous system and are also the target of operative interventions. This review article focuses on the description of these hemodynamic aspects which all physicians involved in the management of dialysis patients should be aware of. Furthermore, it delineates their complicated interactions and also highlights their utility in clinical decision-making and therapeutic management.
