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J Reprod Med ; 31(11): 1045-8, 1986 Nov.
Article in English | MEDLINE | ID: mdl-3543342

ABSTRACT

A double-blind, parallel study was conducted comparing a new imidazole derivative, butoconazole nitrate, with placebo and miconazole nitrate for the treatment of vulvovaginal candidiasis. Patients were randomly assigned to six treatment regimens. Butoconazole was found to be an effective antifungal agent in both the six- and three-day treatment schedules. The incidence of local side effects from both tested imidazoles was low.


Subject(s)
Antifungal Agents/therapeutic use , Candidiasis, Vulvovaginal/drug therapy , Imidazoles/therapeutic use , Miconazole/therapeutic use , Adolescent , Adult , Aged , Antifungal Agents/adverse effects , Clinical Trials as Topic , Dose-Response Relationship, Drug , Double-Blind Method , Female , Humans , Imidazoles/adverse effects , Miconazole/adverse effects , Middle Aged , Ointments
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