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[THE DIFFERENTIAL DIAGNOSTIC OF ANEMIA].
Levina, A A; Mesheryakova, L M; Tsibulskaya, M M; Sokolova, T V.
Klin Lab Diagn ; 60(12): 26-30, 2015 Dec.
Article in Russian | MEDLINE | ID: mdl-27032249

ABSTRACT

The article presents analysis of the publications' data of the recent years concerning regulation of iron metabolism and possibilities of application of indicators of iron metabolism in differential diagnostic of anemia. The original results of protein detection are described concerning bivalent transporter of metals and ferroportine under iron-deficiency anemia, anemia of chronic inflammatory diseases and autoimmune hemolytic anemia. The significance of these proteins in more profound comprehension of pathogenesis is demonstrated


Subject(s)
Anemia, Hemolytic, Autoimmune/diagnosis , Anemia, Iron-Deficiency/diagnosis , Iron/blood , Anemia, Hemolytic, Autoimmune/blood , Anemia, Hemolytic, Autoimmune/genetics , Anemia, Hemolytic, Autoimmune/pathology , Anemia, Iron-Deficiency/blood , Anemia, Iron-Deficiency/genetics , Anemia, Iron-Deficiency/pathology , Cation Transport Proteins/blood , Cation Transport Proteins/genetics , Chronic Disease , Diagnosis, Differential , Ferritins/blood , Ferritins/genetics , Gene Expression Regulation , Hepcidins/blood , Hepcidins/genetics , Humans , Transcription Factors/blood , Transcription Factors/genetics
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