ABSTRACT
Background: Industrial symbiosis (IS) primarily involves interfirm utilization of industrial residual resources. An important factor determining the success of IS is the identification and matching of cooperation opportunities. Digital tools, including IS platforms, are considered facilitators of this process. This systematic literature review addresses the research question: ' Which are the most important data points of an IS platform and how can they be used for the promotion of IS?'. Methods: The review is based on scientific publications from the following academic research databases: ScienceDirect, Scopus, SpringerLink, Wiley Online Library, AISel and IEEE (via Google Scholar), and grey literature obtained through a customized Google search technique, last performed on 9/3/2021. Records were included according to their scientific content, namely if the document: i) examined the identification of synergies utilizing ICT tools, ii) data requirements or platform related information were presented or iii) the impact of a digital tool in promoting IS was discussed. Exclusion criteria were: articles not written in English, not peer-reviewed, published before 2016 or document type other than scientific article, conference paper or EU project deliverable. Two independent reviewers performed title scanning and abstract reading of the documents to reduce the risk of bias. Results: The total number of records included after abstract and full text reading was 32. The main results of this review suggest that two significant types of data points are encountered in IS platforms; i) data required for synergy identification and ii) platform related information. Conclusions: A possible limitation of the study is a minor risk of bias due to one reviewer performing full text reading and synthesis of results; however, they reported to and consulted with the supervising reviewer. Overall, the results indicate that several types of data points are required for effective matching and successful promotion of IS through digital tools.
ABSTRACT
BACKGROUND: Previous studies have shown that in the absence of underlying cardiac pathology, the echocardiographic estimate of right ventricular systolic pressure (RVSP) increases progressively and normally with age. There are limited data in patients older than 60 years of age. OBJECTIVE: To define the ranges of RVSP according to age and to include more elderly patients than have previously been reported. METHODS: All patients undergoing echocardiography since May 26, 1999, at the Kingston Heart Clinic (Kingston, Ontario) have had their data entered into a locally designed cardiology database (CARDIOfile; Registered trademark, Kingston Heart Clinic). RVSP was calculated from the peak tricuspid regurgitant jet velocity (V) using the modified Bernoulli equation (RVSP = 4V2 + RAP), with the mean right atrial pressure (RAP) estimated to be 10 mmHg. Of the 22,628 patients who had undergone echocardiography, 10,905 had RVSP measured. All abnormal echocardiograms were excluded, leaving 1559 echocardiograms for analysis. RESULTS: Patient age ranged from 15 to 93 years. The mean age was 49 years. RVSP increased significantly only after the age of 50 years. The mean (+/- SD) RVSP for those younger than 50 years, 50 to 75 years, and older than 75 years of age was 27.3+/-5.7 mmHg, 30.2+/-7.6 mmHg and 34.8+/-8.7 mmHg, respectively (P<0.0001 among all age groups). The normal range (95% CI) of RVSP in those younger than 50 years, 50 to 75 years, and older than 75 years of age was 16 mmHg to 39 mmHg, 15 mmHg to 45 mmHg, and 17 mmHg to 52 mmHg, respectively. Multivariate analysis indicated that age, mitral diastolic early-to-late filling velocity ratio, ejection fraction, aortic size and early mitral filling velocity/ early diastolic mitral annular velocity were the only significant independent variables. There were significant changes in diastolic function with increasing age, which may have been responsible for the changes in RVSP. CONCLUSIONS: RVSP remains stable in both men and women until the age of 50 years. Thereafter, RVSP increases progressively in a linear manner with age and is significantly higher in patients older than 75 years of age. The changes may relate to changes in diastolic function. These ranges should be taken into account when using echocardiogram-derived RVSP for the diagnosis of pulmonary hypertension in the absence of cardiovascular disease.
