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1.
Heliyon ; 9(10): e20540, 2023 Oct.
Article in English | MEDLINE | ID: mdl-37842622

ABSTRACT

The use of masks as a measure to control the spread of respiratory viruses has been widely acknowledged. However, there are instances where wearing a mask is not possible, making these environments potential vectors for virus transmission. Such environments can contain multiple sources of infection and are challenging to characterize in terms of infection risk. To address this issue, we have developed a methodology to investigate the role of ventilation in reducing the infection risk in such environments. We use a restaurant setting as a representative scenario to demonstrate the methodology. Using implicit large eddy simulations along with discrete droplet dispersion modeling we investigate the impact of ventilation and physical distance on the spread of respiratory viruses and the risk of infection. Our findings show that operating ventilation systems, such as mechanical mixing and increasing physical distance between subjects, can significantly reduce the average room infection risk and number of newly infected subjects. However, this observation is subject to the transmissibility of the airborne viruses. In the case of a highly transmissible virus, the use of mechanical mixing may be inconsequential when compared to only fresh air ventilation. These findings provide valuable insights into the mitigation of infection risk in situations where the use of masks is not possible.

2.
PLoS Comput Biol ; 19(3): e1010972, 2023 03.
Article in English | MEDLINE | ID: mdl-36940207

ABSTRACT

As evidenced by the worldwide pandemic, respiratory infectious diseases and their airborne transmission must be studied to safeguard public health. This study focuses on the emission and transport of speech-generated droplets, which can pose risk of infection depending on the loudness of the speech, its duration and the initial angle of exhalation. We have numerically investigated the transport of these droplets into the human respiratory tract by way of a natural breathing cycle in order to predict the infection probability of three strains of SARS-CoV-2 on a person who is listening at a one-meter distance. Numerical methods were used to set the boundary conditions of the speaking and breathing models and large eddy simulation (LES) was used for the unsteady simulation of approximately 10 breathing cycles. Four different mouth angles when speaking were contrasted to evaluate real conditions of human communication and the possibility of infection. Breathed virions were counted using two different approaches: the breathing zone of influence and direction deposition on the tissue. Our results show that infection probability drastically changes based on the mouth angle and the breathing zone of influence overpredicts the inhalation risk in all cases. We conclude that to portray real conditions, the probability of infection should be based on direct tissue deposition results to avoid overprediction and that several mouth angles must be considered in future analyses.


Subject(s)
COVID-19 , SARS-CoV-2 , Humans , Respiratory System , Administration, Inhalation , Respiration
3.
Sports Biomech ; : 1-15, 2022 Dec 12.
Article in English | MEDLINE | ID: mdl-36510445

ABSTRACT

This study was designed to develop a computational fluid dynamics (CFD) method for unsteady analysis of a series of ski jump movements with attitude changes, and to analyse the aerodynamic characteristics of an expert jumper over the entire ski jump movement. Two ski jumpers participated in this study. A sensor-based motion capture suit was used to capture the jumper's posture during the actual ski jump. A three-dimensional computer graphics animation was created by superimposing the joint angles obtained from the motion measurements of the 3D shape of the athlete. The unsteady aerodynamic forces acting on the ski jumper, from the takeoff to the landing, were then calculated using CFD. A time-varying spatially uniform flow was specified as the inflow boundary condition of the computational domain. The results indicated that both the lift and drag forces of the expert jumper increase rapidly during the initial flight when the jumper's posture changes drastically. Thereafter, drag force decreased considerably, but the decrease in the lift force was less drastic. Later in the flight phase, the lift force acting on the expert jumper increased, and throughout the flight phase, the lift-drag ratio of the expert jumper remained higher than that of the unskilled jumper.

4.
Sci Rep ; 12(1): 15361, 2022 09 13.
Article in English | MEDLINE | ID: mdl-36100616

ABSTRACT

A numerical simulation of sibilant /s/ production with the realistically moving vocal tract was conducted to investigate the flow and acoustic characteristics during the articulation process of velopharyngeal closure and tongue movement. The articulation process was simulated from the end of /u/ to the middle of /s/ in the Japanese word /usui/, including the tongue elevation and the velopharyngeal valve closure. The time-dependent vocal tract geometry was reconstructed from the computed tomography scan. The moving immersed boundary method with the hierarchical structure grid was adopted to approach the complex geometry of the human speech organs. The acoustic characteristics during the co-articulation process were observed and consistent with the acoustic measurement for the subject of the scan. The further simulations with the different closing speeds of the velopharyngeal closure showed that the far-field sound during the co-articulation process was amplified with the slower closing case, and the velum closure speed was inverse proportional to the sound amplitude with the slope value of - 35.3 dB s/m. This indicates possible phonation of indistinguishable aeroacoustics sound between /u/ and /s/ with slower velopharyngeal closure.


Subject(s)
Phonation , Tongue , Acoustics , Humans , Sound , Speech
5.
Sci Rep ; 12(1): 14120, 2022 08 19.
Article in English | MEDLINE | ID: mdl-35986163

ABSTRACT

Dental professionals are at high risk of exposure to communicable diseases during clinical practice, but many dental clinics provide clinical care in closed spaces. Therefore, it is essential to develop efficient ventilation methods in dental clinics that do not rely on natural ventilation. In this study, to clarify the factors that cause air retention in dental offices, we conducted computational flow dynamics simulations focusing on (1) the flow path from the entrance to the exhaust port and (2) the presence of partitions. A three-dimensional model of a dental clinic with three dental chairs was created, and simulations were conducted for scenarios with and without partitions with different entrance and exhaust port positions. Evaluation of these simulations on the basis of the age of air, an indicator of ventilation efficiency, showed that the value of the air age near the partition was locally high in the scenarios with partitions. In the scenarios where the exhaust port was located close to the entrance, the air age near the exhaust port was high, regardless of the presence of a partition. In addition to wearing protective clothing and sterilizing instruments, it is important to consider air quality improvement as a countermeasure against airborne and droplet infections, such as virus infections, in dental clinics.


Subject(s)
Air Pollution, Indoor , Air Pollution , Computer Simulation , Dental Offices , Ventilation/methods
6.
Sci Rep ; 12(1): 11186, 2022 07 01.
Article in English | MEDLINE | ID: mdl-35778513

ABSTRACT

The dose-response model has been widely used for quantifying the risk of infection of airborne diseases like COVID-19. The model has been used in the room-average analysis of infection risk and analysis using passive scalars as a proxy for aerosol transport. However, it has not been employed for risk estimation in numerical simulations of droplet dispersion. In this work, we develop a framework for the evaluation of the probability of infection in droplet dispersion simulations using the dose-response model. We introduce a version of the model that can incorporate the higher transmissibility of variant strains of SARS-CoV2 and the effect of vaccination in evaluating the probability of infection. Numerical simulations of droplet dispersion during speech are carried out to investigate the infection risk over space and time using the model. The advantage of droplet dispersion simulations for risk evaluation is demonstrated through the analysis of the effect of ambient wind, humidity on infection risk, and through a comparison with risk evaluation based on passive scalars as a proxy for aerosol transport.


Subject(s)
COVID-19 , Infections , Administration, Inhalation , Aerosols/adverse effects , Humans , RNA, Viral , SARS-CoV-2
7.
Int J High Perform Comput Appl ; 36(5-6): 568-586, 2022 Nov.
Article in English | MEDLINE | ID: mdl-38603243

ABSTRACT

The fastest supercomputer in 2020, Fugaku, has not only achieved digital transformation of epidemiology in allowing end-to-end, detailed quantitative modeling of COVID-19 transmissions for the first time but also transformed the behavior of the entire Japanese public through its detailed analysis of transmission risks in multitudes of societal situations entailing heavy risks. A novel aerosol simulation methodology was synthesized out of a combination of a new CFD methods meeting industrial demands in the solver, CUBE (Jansson et al., 2019), which not only allowed the simulations to scale massively with high resolution required for micrometer virus-containing aerosol particles but also enabled extremely rapid time-to-solution due to its ability to generate the digital twins representing multitudes of societal situations in a matter of minutes, attaining true overall application high performance; such simulations have been running for the past 1.5°years on Fugaku, cumulatively consuming top supercomputer-class resources and the communicated by the media as well as becoming the basis for official public policies.

8.
Sci Rep ; 11(1): 16720, 2021 08 18.
Article in English | MEDLINE | ID: mdl-34408209

ABSTRACT

The effects of the inclination angle of the incisor on the speech production of the fricative consonant /s/ was investigated using an implicit compressible flow solver. The hierarchical structure grid was applied to reduce the grid generation time for the vocal tract geometry. The airflow and sound during the pronunciation of /s/ were simulated using the adaptively switched time stepping scheme, and the angle of the incisor in the vocal tract was changed from normal position up to 30°. The results showed that increasing the incisor angle affected the flow configuration and moved the location of the high turbulence intensity region thereby decreased the amplitudes of the sound in the frequency range from 8 to 12 kHz. Performing the Fourier transform on the velocity fluctuation, we found that the position of large magnitudes of the velocity at 10 kHz shifted toward the lip outlet when the incisor angle was increased. In addition, separate acoustic simulations showed that the shift in the potential sound source position decreased the far-field sound amplitudes above 8 kHz. These results provide the underlying insights necessary to design dental prostheses for the production of sibilant fricatives.

9.
Flow Turbul Combust ; 99(3): 837-864, 2017.
Article in English | MEDLINE | ID: mdl-30069160

ABSTRACT

Large-eddy simulations are conducted for a rotating golf ball and a rotating smooth sphere at a constant rotational speed at the subcritical, critical and supercritical Reynolds numbers. A negative lift force is generated in the critical regime for both models, whereas positive lift forces are generated in the subcritical and supercritical regimes. Detailed analysis on the flow separations on different sides of the models reveals the mechanism of the negative Magnus effect. Further investigation of the unsteady aerodynamics reveals the effect of rotating motion on the development of lateral forces and wake flow structures. It is found that the rotating motion helps to stabilize the resultant lateral forces for both models especially in the supercritical regime.

10.
J Biomech ; 49(15): 3688-3696, 2016 11 07.
Article in English | MEDLINE | ID: mdl-27743629

ABSTRACT

The purpose of this study was to investigate the effects of posture of a ski jumper on aerodynamic characteristics during the take-off using computational fluid dynamics (CFD). The CFD method adopted for this study was based on Large-Eddy Simulation. Body surface data were obtained by 3-D laser scanning of an active ski jumper. Based on video analysis of the actual take-off movement, two sets of motion data were generated (world-class jumper A and less-experienced jumper B). The inlet flow velocity that corresponds to the in-run velocity in actual ski jumping was set to 23.23m/s in the CFD. The aerodynamic force, flow velocity, and vortexes for each model were compared between models. The total drag force acting upon jumper A was lower than that acting upon jumper B through the whole movement. Regarding the total lift force, although jumper A׳s total lift force was less in the in-run posture, it became greater than that of jumper B at the end of the movement. In the latter half of the movement, low air-speed domain expansion was observed at the model׳s back. This domain of jumper B was larger. There were two symmetric vortexes in the wake of jumper A, but the disordered vortexes were observed behind the jumper B. In the case of jumper A, these two distinct vortexes generated by the arms produced a downwash flow in the wake. It is considered that the positioning of the arms in a very low position strongly influences the flow structure.


Subject(s)
Posture/physiology , Skiing/physiology , Adolescent , Adult , Arm/physiology , Biomechanical Phenomena , Female , Humans , Male , Models, Theoretical , Movement/physiology , Young Adult
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