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1.
J Bone Joint Surg Am ; 87 Suppl 1(Pt 2): 292-9, 2005 Sep.
Article in English | MEDLINE | ID: mdl-16140802

ABSTRACT

BACKGROUND: In 1981, we developed a technique of expansive lumbar laminoplasty to alleviate the problems of conventional laminectomy in the treatment of spinal stenosis. The purposes of this study were to assess the long-term outcome following expansive lumbar laminoplasty and to investigate the postoperative problems. METHODS: Fifty-four patients underwent expansive lumbar laminoplasty for the treatment of spinal stenosis. There were forty-three men and eleven women with a mean age of 52.6 years. The average length of follow-up was 5.5 years. Preoperatively, twenty-five patients had degenerative stenosis; thirteen, stenosis due to spondylolisthesis; twelve, combined stenosis (disc herniation and stenosis); and six, hyperostotic stenosis. (Two patients with hyperostotic stenosis and spondylolisthesis were included in both groups.) The clinical results were assessed with use of the Japanese Orthopaedic Association score, and the rate of recovery was calculated. Radiographic findings were analyzed on the basis of the cross-sectional area of the spinal canal, kyphosis, range of motion of the lumbar spine, and the rate of interlaminar fusion. RESULTS: The average recovery rate at the time of the last follow-up was 69.2% for patients with degenerative stenosis, 66.5% for patients with combined stenosis, 65.2% for those with hyperostotic stenosis, and 54.7% for those with spondylolisthesis. The factors resulting in a poor recovery were an older age and insufficient decompression of the lateral stenosis. During the follow-up period, the Japanese Orthopaedic Association score became worse for seven patients, six patients had lesions develop at the level adjacent to the laminoplasty, and five patients had spondylolisthesis develop. Interlaminar fusion was observed in twenty-two patients (41%). CONCLUSIONS: The satisfactory results of expansive lumbar laminoplasty were maintained at an average of 5.5 years after surgery. The best indications for the lumbar laminoplasty procedure were young and active patients with central spinal stenosis.


Subject(s)
Bone Transplantation/methods , Laminectomy/methods , Spinal Stenosis/surgery , Female , Humans , Male , Middle Aged , Radiography , Plastic Surgery Procedures/methods , Spinal Stenosis/diagnostic imaging
2.
J Bone Joint Surg Am ; 86(8): 1698-703, 2004 Aug.
Article in English | MEDLINE | ID: mdl-15292417

ABSTRACT

BACKGROUND: In 1981, we developed a technique of expansive lumbar laminoplasty to alleviate the problems of conventional laminectomy in the treatment of spinal stenosis. The purposes of this study were to assess the long-term outcome following expansive lumbar laminoplasty and to investigate the postoperative problems. METHODS: Fifty-four patients underwent expansive lumbar laminoplasty for the treatment of spinal stenosis. There were forty-three men and eleven women with a mean age of 52.6 years. The average length of follow-up was 5.5 years. Preoperatively, twenty-five patients had degenerative stenosis; thirteen, stenosis due to spondylolisthesis; twelve, combined stenosis (disc herniation and stenosis); and six, hyperostotic stenosis. (Two patients with hyperostotic stenosis and spondylolisthesis were included in both groups.) The clinical results were assessed with use of the Japanese Orthopaedic Association score, and the rate of recovery was calculated. Radiographic findings were analyzed on the basis of the cross-sectional area of the spinal canal, kyphosis, range of motion of the lumbar spine, and the rate of interlaminar fusion. RESULTS: The average recovery rate at the time of the last follow-up was 69.2% for patients with degenerative stenosis, 66.5% for patients with combined stenosis, 65.2% for those with hyperostotic stenosis, and 54.7% for those with spondylolisthesis. The factors resulting in a poor recovery were an older age and insufficient decompression of the lateral stenosis. During the follow-up period, the Japanese Orthopaedic Association score became worse for seven patients, six patients had lesions develop at the level adjacent to the laminoplasty, and five patients had spondylolisthesis develop. Interlaminar fusion was observed in twenty-two patients (41%). CONCLUSIONS: The satisfactory results of expansive lumbar laminoplasty were maintained at an average of 5.5 years after surgery. The best indications for the lumbar laminoplasty procedure were young and active patients with central spinal stenosis.


Subject(s)
Laminectomy/methods , Spinal Stenosis/surgery , Adult , Aged , Female , Follow-Up Studies , Humans , Male , Middle Aged , Radiography , Spinal Stenosis/diagnostic imaging , Treatment Outcome
3.
J Chromatogr A ; 1014(1-2): 103-7, 2003 Oct 03.
Article in English | MEDLINE | ID: mdl-14558616

ABSTRACT

Separation and on-line concentration of bisphenol A and three alkylphenols were investigated by micellar electrokinetic chromatography with the anionic surfactant, sodium dodecyl sulfate. The separation conditions were optimized by the simultaneous addition of the organic solvent and cyclodextrin to the running solution. The separation of hydrophobic analytes and 4-nonylphenol isomers was improved by the addition of 10% methanol and 5 mM beta-cyclodextrin to the running solution. When the sweeping with the running solution was used as the on-line concentration procedure, 69-, 48-, 55- and 41-fold increases in detection sensitivity were obtained for bisphenol A, 4-tert.-butylphenol and 4-(1,1,3,3-tetramethylbutyl)phenol, and the second peak of 4-nonylphenol isomers, respectively. The detection limits were 0.0071, 0.0065, 0.021 and 0.055 mg/l, respectively. These results were better than those with the cationic surfactant, tetradecyltrimethylammonium bromide.


Subject(s)
Chromatography, Micellar Electrokinetic Capillary/methods , Phenols/analysis , Surface-Active Agents/chemistry , Benzhydryl Compounds , Sensitivity and Specificity
4.
J Chromatogr A ; 979(1-2): 425-9, 2002 Dec 06.
Article in English | MEDLINE | ID: mdl-12498274

ABSTRACT

The separation and on-line concentration of bisphenol A and three alkylphenols were investigated by micellar electrokinetic chromatography with cationic surfactant. Tetradecyltrimethylammonium bromide was used as surfactant and the separation conditions were optimized by the addition of the organic solvents and cyclodextrins to the running solution. The separation of hydrophobic analytes and 4-nonylphenol isomers was improved by the addition of 20% acetonitrile and 20 mM beta-cyclodextrin to the running solution. When the sweeping with the running solution used as the on-line concentration procedure, 56-, 67- and 29-fold increase in detection sensitivity of bisphenol A, 4-tert.-butylphenol and 4-(1,1,3,3-tetramethylbutyl)phenol, respectively. The detection limits were 0.030, 0.098 and 0.159 mg/l, respectively.


Subject(s)
Chromatography, Micellar Electrokinetic Capillary/methods , Phenols/isolation & purification , Surface-Active Agents/analysis , Benzhydryl Compounds , Cations , Cyclodextrins/chemistry , Phenols/chemistry , Sensitivity and Specificity , Solvents/chemistry
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