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1.
Respir Care ; 2024 Jul 09.
Article in English | MEDLINE | ID: mdl-38981654

ABSTRACT

BACKGROUND: A model system described in International Organization for Standardization 9360 is the standard method for estimating the humidifying performance of heat-and-moisture exchangers (HMEs). However, there are no reliable bedside methods for evaluating the ongoing humidification performance of HMEs. Therefore, this study aimed to develop 2 clinically applicable methods for estimating the ongoing humidifying performance of HMEs and to evaluate their reliability in a model system. METHODS: Physiologically expired gas was simulated using a heated humidifier, and ventilation was delivered using a ventilator with constant flow through 3 different types of HMEs. Relative humidity (RH) was measured using a capacitive-type moisture sensor. Water content lost during expiration was calculated by integrating absolute humidity (AH), instantaneous gas flow measured at the expiratory outlet of the ventilator, and time. We also calculated the water content released and captured by the HMEs during tidal ventilation by integrating the difference in AH across the HMEs, instantaneous gas flow, and time. RESULTS: We found that the RH, temperature, and AH were almost constant on the expiratory outlet of the ventilator but rapidly varied near the HMEs. The water content lost by the 3 HMEs was associated with the manufacturer-reported values and inversely correlated with the calculated values of the water content exchanged by the HMEs. The water content released and captured by HMEs was closely correlated with the difference in HME weight measured at the end of inspiration and expiration; however, the water content captured by HMEs seemed to be overestimated. CONCLUSIONS: Our results demonstrated that our system was able to detect the differences in the performance of 3 models of HMEs and suggest that our method for calculating water loss is reliable for estimating the water retention performance of HMEs during mechanical ventilation, even in the presence of a constant flow.

2.
Sci Rep ; 12(1): 8291, 2022 May 25.
Article in English | MEDLINE | ID: mdl-35614103

ABSTRACT

The elastic-wave scattering at interfaces, such as cracks, is essential for nondestructive inspections, and hence, understanding the phenomenon is crucial. However, the elastic-wave scattering at cracks is very complex in three dimensions since microscopic asperities of crack faces can be multiple scattering sources. We propose a method for exploring 3D elastic-wave scattering based on our previously developed high-resolution 3D phased-array system, the piezoelectric and laser ultrasonic system (PLUS). We describe the principle of PLUS, which combines a piezoelectric transmitter and a 2D mechanical scan of a laser Doppler vibrometer, enabling us to resolve a crack into a collection of scattring sources. Subsequently, we show how the 3D elastic-wave scattering in the vicinity of each response can be extracted. Here, we experimentally applied PLUS to a fatigue-crack specimen. We found that diverse 3D elastic-wave scattering occurred in a manner depending on the responses within the fatigue crack. This is significant because access to such information will be useful for optimizing inspection conditions, designing ultrasonic measurement systems, and characterizing cracks. More importantly, the described methodology is very general and can be applied to not only metals but also other materials such as composites, concrete, and rocks, leading to progress in many fields.

3.
Ultrasonics ; 119: 106629, 2022 Feb.
Article in English | MEDLINE | ID: mdl-34700266

ABSTRACT

Crack closure can cause the underestimation or misdetection of fatigue cracks in ultrasonic testing (UT). Fatigue-crack closure due to an environmental factor, i.e., high temperature, was found in eddy current testing (ECT), which is used to inspect the vicinity of surfaces. However, its effect and countermeasures have yet to be examined in UT. In this study, we examined the fatigue-crack closure induced by heat processing using a surface-acoustic-wave phased array (SAW PA). SAW PA is a phased-array imaging method using Rayleigh waves, which can sensitively visualize defects in the vicinity of surfaces. As a result, the intensity of crack responses visualized by SAW PA markedly decreased after the heat processing of a fatigue-crack specimen. Furthermore, we demonstrated that the combination of SAW PA with a crack opening method, global preheating and local cooling (GPLC), and a load difference phased array (LDPA) is useful for the high-selectivity imaging of closed fatigue cracks. We also discussed a possible mechanism of the fatigue-crack closure induced by heat processing.

4.
Sensors (Basel) ; 21(21)2021 Oct 22.
Article in English | MEDLINE | ID: mdl-34770316

ABSTRACT

The nondestructive inspection of concrete structures is indispensable for ensuring the safety and reliability of aging infrastructures. Ultrasonic waves having a frequency of tens of kHz are frequently used to reduce the scattering attenuation due to coarse aggregates. Such low frequencies enable the measurement of the thickness of concrete structures and detection of layer-type defects, such as delamination, whereas it causes a lack of sensitivity to crack-type defects. In this paper, to realize the ultrasonic phased array (PA) imaging of crack-type defects, we fabricated a low-frequency (LF) array transducer with a center frequency of hundreds of kHz. To avoid the crosstalk between piezoelectric elements and dampen the vibration of each element, we adopted soft lead zirconate titanate (soft PZT) with a low mechanical quality factor. Subsequently, we optimized the geometry of each piezoelectric element using a finite element method to generate a short pulse. After validating the design in a fundamental experiment using a single-element transducer, we fabricated a 32-element array transducer with a center frequency of 350 kHz. To show the imaging capability of the LF array transducer, we applied it to a concrete specimen with a delamination. As a result, the PA with the LF array transducer clearly visualized the delamination, which could not be visualized using the PA with a 2.5 MHz array transducer. Furthermore, we applied it to a more challenging defect, a slit, which is sometimes used to simulate crack-type defects. As a result, the PA with the LF array transducer clearly visualized a slit of 1 mm width and 40 mm height in a concrete specimen. Thus, we demonstrated the usefulness of the LF array transducer for inspecting crack-type defects.

5.
J Acoust Soc Am ; 146(1): 266, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31370588

ABSTRACT

The nondestructive evaluation of closed cracks is a challenging subject in ultrasonic testing. Recently, nonlinear ultrasonic phased array with fixed-voltage fundamental wave amplitude difference (fixed-voltage FAD) has been proposed as a practical approach. In this study, the maximum incident wave amplitude, which is one of the most critical parameters in closed-crack imaging, was investigated. First, a theoretical model was formulated to explicitly show the essence of the fundamental principle of FAD and the advantage of fixed-voltage FAD over different-voltage FAD. In experiments, the authors imaged a closed fatigue crack using a nonlinear ultrasonic phased array with fixed-voltage FAD while varying the incident wave amplitude. It was found that when the incident wave amplitude was sufficiently high, the nonlinear image visualized the closed crack tip, which could not be visualized in linear images. In addition, the incident-wave-amplitude dependence of the nonlinear responses was quantified. It was found that different parts within a single fatigue crack showed different nonlinear behaviors. This suggests that fixed-voltage FAD is useful not only for practical application of closed crack imaging but also for examining the nonlinear dynamics at various parts of closed cracks with a high spatial resolution.

6.
Sensors (Basel) ; 18(10)2018 Oct 13.
Article in English | MEDLINE | ID: mdl-30322123

ABSTRACT

When inert gas containing water molecules flows into a metal pipe, the water molecules cannot exit instantaneously from the outlet of the pipe but are captured at adsorption sites on the inner surface of the pipe until most of the sites are occupied. A theoretical model and a subsequent experiment in this article show that the delay time depends on the amount of moisture level; the higher the moisture-level, the shorter the delay time. Based on the result, we propose a new method and its implementation to the validation of a standard moisture generation to be used in the field measurement such as in factories and pipe lines.

7.
Rev Sci Instrum ; 89(5): 055006, 2018 May.
Article in English | MEDLINE | ID: mdl-29864824

ABSTRACT

The measurement and control of trace moisture, where the water concentration is lower than 1 ppmv [-76.2 °C for the frost point (°CFP)], are essential for improving the yield rate of semiconductor devices and for ensuring their reliability. A ball surface acoustic wave (SAW) sensor with a sol-gel silica coating exhibited useful characteristics for a trace moisture analyzer (TMA) when the temperature drift of the delay time output was precisely compensated using two-frequency measurement (TFM), where the temperature-compensated relative delay time change (RDTC) was obtained by subtracting the RDTC at the fundamental frequency from that at the third harmonic frequency on an identical propagation path. However, the cost of the measurement circuit was a problem. In this study, a burst waveform undersampling (BUS) circuit based on the theory of undersampling measurement was developed as a practical means. The BUS circuit was useful for precise temperature compensation of the RDTC, and the ball SAW TMA was prototyped by calibrating the RDTC using a TMA based on cavity ring-down spectroscopy (CRDS), which is the most reliable method for trace moisture measurement. The ball SAW TMA outputted a similar concentration to that obtained by the CRDS TMA, and its response time at a set concentration in N2 with a flow rate of 1 l/min was about half that of the CRDS TMA, suggesting that moisture of -80 °CFP was measured within only 1 min. The detection limit at a signal-to-noise ratio of 3 was estimated to be 0.05 ppbv, comparable with that of the CRDS TMA. From these results, it was demonstrated that a practical ball SAW TMA can be realized using the developed BUS circuit.

8.
Rev Sci Instrum ; 78(10): 103703, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17979424

ABSTRACT

To improve the precision of dynamic atomic force microscopy (AFM) using cantilever vibration spectra, a simple but effective method for suppressing spurious response (SR) was developed. The dominant origin of SR was identified to be the bending vibration of the cantilever substrate, by the analysis of the frequency of SR. Although a rigid cover pressing the whole surface of the substrate suppressed SR, the utility was insufficient. Then, a method of enhancing the bending rigidity of the substrate by gluing a rigid plate (clamping plate, CP) to the substrate was developed. This chip can be used with an ordinary cantilever holder, so that the reproducibility of SR suppression when attaching and detaching the cantilever chip to the holder was improved. To verify its utility, the evaluation of a microdevice electrode was performed by ultrasonic atomic force microscopy. The delamination at a submicron depth was visualized and the detailed variation of the delamination was evaluated for the first time using clear resonance spectra. The CP method will particularly contribute to improving dynamic-mode AFM, in which resonance spectra with a low quality factor are used, such as noncontact mode AFM in liquid or contact resonance mode AFM. The effect of the CP can be achieved by fabricating a substrate with a thick plate beforehand.


Subject(s)
Artifacts , Image Enhancement/instrumentation , Microscopy, Atomic Force/instrumentation , Specimen Handling/instrumentation , Transducers , Elasticity , Equipment Design , Equipment Failure Analysis , Image Enhancement/methods , Microscopy, Atomic Force/methods , Reproducibility of Results , Sensitivity and Specificity , Specimen Handling/methods , Stress, Mechanical , Vibration
9.
Plant Cell Physiol ; 45(2): 225-31, 2004 Feb.
Article in English | MEDLINE | ID: mdl-14988493

ABSTRACT

Multiprotein bridging factor 1 (MBF1) is known to be a transcriptional co-activator that mediates transcriptional activation by bridging between an activator and a TATA-box binding protein (TBP). We demonstrated that expression of every three MBF1 from Arabidopsis partially rescues the yeast mbf1 mutant phenotype, indicating that all of them function as co-activators for GCN4-dependent transcriptional activation. We also report that each of their subtypes shows distinct tissue-specific expression patterns and responses to phytohormones. These observations suggest that even though they share a similar biochemical function, each MBF1 has distinct roles in various tissues and conditions.


Subject(s)
Arabidopsis/genetics , Arabidopsis/metabolism , Plant Proteins , Trans-Activators/biosynthesis , Trans-Activators/genetics , Transcriptional Activation/genetics , Arabidopsis Proteins/biosynthesis , Arabidopsis Proteins/genetics , Arabidopsis Proteins/isolation & purification , Basic-Leucine Zipper Transcription Factors , DNA, Complementary/analysis , DNA, Complementary/genetics , DNA-Binding Proteins/genetics , DNA-Binding Proteins/metabolism , Fungal Proteins/genetics , Gene Expression Regulation, Plant/genetics , Glutathione Transferase/metabolism , Macromolecular Substances , Molecular Sequence Data , Mutation/genetics , Nuclear Proteins/genetics , Nuclear Proteins/metabolism , Open Reading Frames/genetics , Plant Growth Regulators/metabolism , Plant Growth Regulators/pharmacology , Protein Binding/genetics , Protein Isoforms/biosynthesis , Protein Isoforms/genetics , Protein Isoforms/isolation & purification , Protein Kinases/genetics , Protein Kinases/metabolism , RNA, Messenger/genetics , Saccharomyces cerevisiae Proteins/genetics , Saccharomyces cerevisiae Proteins/metabolism , Sequence Homology, Amino Acid , Sequence Homology, Nucleic Acid , TATA-Box Binding Protein/genetics , TATA-Box Binding Protein/metabolism , Trans-Activators/isolation & purification , Transcription Factors/genetics , Transcription Factors/metabolism
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