[Changes in trends of diseases requiring long-term care in an aging community].

Objectives　The purpose of this study was to identify the changes in trends of leading diseases that require long-term care within a 5-year period in an area with a rapidly growing aging population.Methods　Data were obtained from newly registered primary insured individuals for long-term care insurance in Sapporo Minami Ward. There were 2,538 participants in FY2018 and 4,089 in FY2013 and FY2014.　Disorders diagnosed by a primary doctor were categorized into groups using a long-term care questionnaire survey from the Comprehensive Survey of Living Conditions. The difference in the frequency of diseases between the survey years was examined using a chi-square test.Results　In men, there was no significant change in the frequency of diseases that require long-term care within the 5-year period. In women, the frequency of cerebrovascular diseases significantly reduced (7.8% for FY2013 and 2014 vs. 5.6% for FY2018; P=0.008) and fractures and falls significantly increased (9.5% vs. 13.8%; P=0.001).　Regarding the diseases in the severe-level category of long-term care insurance, malignancy was the most frequent disorder in men, followed by stroke. In women, the frequency of fractures and falls increased (10.5% vs. 17.7%; P=0.002) and subsequently became the most frequently occurring disorder. Similarly, the frequency of fractures and falls increased significantly (9.2% vs. 12.5%; P=0.004) in the mild-level long-term care insurance category.Conclusion　For women, fractures and falls increased within the 5-year period, indicating the need to introduce a prompt preventive program. Lifestyle-related diseases such as malignancy and cerebrovascular diseases have become the main reason for shortening a healthy lifespan. This finding highlights the importance of preventing lifestyle-related diseases.

[Diseases requiring severe-level care certification for long-term care insurance].

Objectives　Extending health expectancy is important; however, health and welfare programs in local areas and communities present their own issues. This study aimed to identify main diseases requiring severe-level care certification for long-term care insurance based on information gathered from opinion papers prepared by primary doctors.Methods　Data were obtained for 4,089 patients aged ≧65 years who were certified for long-term care insurance for the first time between April 1, 2013, and March 31, 2015. Their disorders were categorized into the groups used in the Comprehensive Survey of Living Conditions long-term care questionnaire. The subjects were categorized into "mild" and "severe" groups according to their long-term care insurance levels. Subjects in the severe group were long-term care insurance levels 2-5. The associations with diseases in the two groups were examined using chi-square tests according to gender. Multiple logistic regression analyses were conducted for those diseases which showed significant associations by chi-square test for the dependent variables after adjusting for age.Results　Malignancy was the most frequent disorder in men, whereas joint disease was most frequent in mild group women. In men, there was a significant difference in the frequency of diseases between the mild and severe groups for stroke (P<0.001), malignancy (P<0.001), joint disease (P<0.001), diabetes (P=0.015), fracture and falls (P=0.028), and others (P<0.001) by chi-square tests. In women, there was a significant difference in the frequency of diseases between the mild and severe groups for stroke (P<0.001), malignancy (P<0.001), joint disease (P<0.001), dementia (P<0.001), Parkinson's disease (P=0.003), and others (P<0.001). In men, multivariate logistic regression analysis revealed that stroke, malignancy, and fracture and falls were significantly and positively associated with severe-level, long-term care insurance, while joint disease and hypertension were negatively associated. In women, stroke, malignancy, dementia, and Parkinson's disease were significantly associated with severe long-term care insurance level, while joint disease and hypertension were negatively associated.Conclusion　The main diseases requiring severe-level care in both men and women were stroke and malignancy. These diseases occurred in large numbers among those less than 74 years of age. This finding suggests the importance of preventing lifestyle-related diseases before the age of 65 years in order to avoid requiring nursing care.

[Differences in factors associated with health checkup participation between persons with differing income levels. A cross-sectional analysis using residential taxation as a measure of household income].

OBJECTIVES: Health insurers in Japan are required to provide health checkups specifically designed to detect signs of metabolic syndrome. Since National Health Insurance organizations have been increasing their numbers of low-income beneficiaries, this observational study was carried out to investigate the differences between persons with differing household income levels based on the factors associated with their participation in health checkups. METHODS: The data source for this study was a database of scored answers in collected, unsigned questionnaires provided by the National Health Insurance of Sapporo City. The survey was conducted in 2009, approaching 3000 beneficiaries aged 40-74 years and sampling 4 groups divided by household income and participation in the 2008 health checkup. The survey included questions about demographics, awareness of the details of the health checkup, and knowledge of lifestyle-related diseases. Valid answers from 1656 respondents were analyzed using multiple logistic regression analysis. RESULTS: After analyzing the level of awareness of health checkup details among subjects and its association with checkup participation, knowledge of the locations where the checkups were held showed the highest adjusted odds ratios. Multivariate logistic regression analysis showed that the following factors were associated with participation in checkups in both lower- and higher-income groups: previous and regular participation in health checkups, willingness to attend the next checkup, and status of family or friends regarding checkup participation. In addition, that a substantial out-of-pocket cost for the checkup was not levied had a significant relationship with checkup attendance in lower-income beneficiaries, while personal obligation to undergo regular health checkups regardless of the busyness of their schedules was found to have a significant relationship in higher-income beneficiaries. In addition, logistic models that excluded factors of previous and future health checkup participation indicated that participation in health checkups in the lower-income group was associated with an interest in health checkup test items, smoking habits, and the perception of the importance of undergoing health checkups even without specific symptoms, while an interest in healthy lifestyles was found to have a significant relationship with participation in health checkups in the higher-income group. CONCLUSION: The study showed that awareness of checkup locations and regular attendance at health check-ups are strongly related to participation. Some differences in factors associated with health checkup participation were detected among individuals with differing income levels.

[Association between clustered strain of M. tuberculosis and infectiousness index of tuberculosis cases in a population-based IS6110-RFLP analysis].

OBJECTIVE: Isolates of M. tuberculosis were analyzed for their DNA fingerprints to facilitate understanding of ongoing transmission of tuberculosis in Sapporo (population 1.87 million), Japan, where the incidence rate of tuberculosis was 15.0 per 100,000 in 2004. SUBJECT: Out of all tuberculosis patients registered in the city from November 1998 to December 2003, isolates from culture-positive respiratory tuberculosis cases for whom written informed consent had been obtained, were analyzed by restriction fragment length polymorphism (RFLP). The study included 345 cases (249 men and 96 women) whose isolates were available for DNA patterns. METHOD: Using standard IS6110-RFLP typing, cases whose isolates shared identical fingerprints were considered to belong to the same cluster. Proportions of clustered cases were evaluated according to their clinical and socio-economical characteristics. RESULTS: Out of 345 cases, 207 (60.0%) were classified into 59 clusters, and 15% of clustered cases having definite epidemiological links. Multiple logistic regression analysis in men showed that age and infectiousness were significantly related to clustering. The adjusted odds ratios (OR) [95% confidence intervals (CI)] were 0.17 [0.03-0.79] for 30-59 years, 0.15 [0.03-0.69] for 60 years or over and 2.35 [1.17-4.70] for those cases assigned as the highest level of transmission of tuberculosis from the infectiousness index of cases. For women the final model showed the adjusted OR [95% CI] were 0.52 [0.22-1.22] for those with previous history of tuberculosis and 0.33 [0.06-1.85] for diabetics. In male cases with a previous history of tuberculosis, most highly infectious cases were significantly associated with clustering (OR [95% CI], 4.53 [1.16-17.68]). CONCLUSION: The results suggest that highly infectious male tuberculosis cases with endogenous reactivation have contributed to recent transmission of tuberculosis in the studied area.

[Tuberculin skin test reaction of health-care workers exposed to tuberculosis infection].

OBJECTIVE: The objective of this study was to describe tuberculin skin test (TST) of health-care workers who had had contacts with a tuberculosis patient and to investigate whether the distributions of the size of TST were different by sputum-smear status of index cases and medical procedures done to the patient. SUBJECTS: Health-care workers who were exposed to tuberculosis infection through contact with patients before diagnosis of tuberculosis were included in this study. Index cases had pulmonary tuberculosis with positive sputum smear and were registered at Sapporo Public Health Office from April 2001 to March 2002. Subjects without past history of BCG (bacilli Calmette-Guerin) vaccinacion were excluded, and final study subjects were 415 (52 male and 363 female, mean age 29.1 years). METHOD: Characteristics of index cases and contact status were obtained from the registration cards of tuberculosis cases at Sapporo Public Health Office. Subjects were divided into two or more categories by the characteristics of index cases and the contact status. Distributions of TST of the subjects in different categories were compared. RESULTS: Contacts with patients received tracheal aspiration showed significantly larger TST reaction than contacts with patients not receiving tracheal aspiration. Among contacts with patients showing minimum to moderately positive sputum-smear, TST reaction was significantly larger in contacts with patients received tracheal aspiration (mean diameter of erythema 35.8 mm) than those not receiving tracheal aspiration (24.8 mm). In contrast, among contacts with patients of severely positive sputum-smear, TST reaction was not significantly different between contacts of patients received tracheal aspiration (35.3 mm) and not receiving tracheal aspiration (33.1 mm). CONCLUSION: TST was significantly stronger in contacts with a tuberculosis patient received tracheal aspiration, which indicates medical procedures such as tracheal aspiration increases the risk of tuberculosis infection in health-care workers.

Urinary catecholamines and salivary cortisol on workdays and days off in relation to job strain among female health care providers.

OBJECTIVES: This study examined the effects of psychosocial job strain on the excretion of neuroendocrine stress hormones (adrenaline, noradrenaline, and cortisol) on workdays and days off. METHODS: Japanese female health care providers (N=16) filled out Karasek's job content questionnaire and had their neuroendocrine excretions (ie, urinary catecholamines and salivary cortisol) measured on a day off and on two workdays (one day shift and one night shift). After control for age and job experience as covariates, a repeated-measures analysis of variance was carried out. RESULTS: Noradrenaline excretion was significantly greater over time in the high-strain group than in the low-strain group, and that of the high-demand group was significantly greater over time than that of the low-demand group. Adrenaline excretion did not significantly differ between the groups. The group with high supervisory support had significantly higher adrenaline excretion than the group with low supervisory support. The concentration of salivary cortisol on a dayshift was significantly lower, but marginally, in the high-strain group than in the low-strain group. CONCLUSIONS: Psychosocial job strain is associated with greater noradrenaline excretion over time. This finding suggests unwinding sympathetic nervous activity. The low cortisol levels of the high-strain group may indicate circadian rhythm disturbance induced by job strain. Supervisory relationships may have a particular influence for the studied occupation because the participants had more administrative contact with supervisors than support at the worksite; therefore, supervisory support may increase adrenaline excretion.

Interpersonal conflict, social support, and burnout among home care workers in Japan.

To examine associations between interpersonal relationships in work settings and burnout, a cross-sectional survey was conducted on home care workers in Sapporo, Japan, by using the Maslach Burnout Inventory (MBI) and scales of interpersonal conflict and social support developed by the authors. Questionnaires were distributed among 303 subjects and returned by 243 subjects (80%). Complete answers were obtained from 106 subjects and were used for analysis. In multiple regression analyses, conflict with clients and their families significantly related to emotional exhaustion and depersonalization of the MBI (p<.05). Supervisory conflict significantly related to emotional exhaustion (p<.05), whereas coworker conflict significantly associated with depersonalization (p<.01). It is suggested that conflicts with clients' families, as well as clients, are important indicators for emotional exhaustion and depersonalization of home care workers.

[Job characteristics and problems related to home care services for the elderly. A comparison among employment categories in Sapporo].

OBJECTIVE: The aims of this study were to describe job characteristics for daytime and shift workers in home care services for the elderly and to clarify health care in the work setting, social support, and job satisfaction and possibilities. METHODS: A self-reported questionnaire was given to 433 home care workers, both full time and part time (more than 15 hours), at 35 institutions that provide home care services to residents of Sapporo (return rate; 80.2%). The following issues were investigated: job content (physical care, assistance with housework, and advice), specialty, job satisfaction, possibilities, job training, health care and social support. The results were compared among employed types: full-time and part-time daytime and shift workers using the t-test or the Fisher's test. RESULTS: The participants demonstrated high dissatisfaction with wages, physical uneasiness themselves and limited social support from their supervisors. Especially full-time workers were dissatisfied with the payment, whereas part-time workers complained about insufficient attention to the prevention of lumbago. It was found that part-time daytime workers were given insufficient on-job-training and education for prevention of infection, and that full-time shift workers greatly wished to leave the employment. However, the home care workers were satisfied with their job itself and expected to continue their work. Furthermore, half of the part-time workers hoped to work full time. CONCLUSIONS: Health management and educational training for part-time workers may be necessary to improve the quality of care services and protection of health. Promotion of full time employment and reconsideration of working condition might be necessary to provide sufficient home care services.

Visual dysfunction in workers exposed to a mixture of organic solvents.

The aim of this study was to investigate the relationship between the workers occupationally exposed to a mixture of organic solvents and their visual functions. Here the visual functions included color vision (CV), visual contrast sensitivity (CS) and visual evoked potentials (VEP). Test subjects were 182 workers at 53 furniture factories in the same industrial area of Japan. As control, a group consisted of 96 workers without exposure to any organic solvent was also tested. Exposure assessments were made both by the environmental concentration and biological monitoring. CV and CS tests were carried out for all the subjects. VEP was measured for 21 exposed subjects who were considered to have impaired CV and CS. In the results, the color confusion index (CCI) values of the exposed subjects were significantly higher than that of the age-matched controls (P<0.01). Their CS values were significantly lower than those in the controls at spatial frequencies of 6 and 12 cycles per degree (cpd) (P<0.01 and <0.05, respectively). A significant correlation between the concentration of urinary methylhippuric acid and contrast sensitivity was found by a multiple regression analysis (P<0.05). CCI showed a negative correlation at all spatial frequencies of CS in a simple regression analysis, no abnormal data were found by the VEP test in the exposed subjects who were found to have impaired CV and CS. The results suppose that a low concentration of the mixed organic solvents might affect the retina and optic nerve. However, it needs to be further researched if such an impact affects the Brodmann's areas of visual cortex in the brain.

Cranial computed tomography associated with development of functional dependence in a community-based elderly population.

OBJECTIVE: To investigate whether changes at computed tomography (CT) imaging in the ageing brain are associated with future risks for functional dependence. SUBJECTS: 160 residents aged 69 years and older at the cranial CT and were independently living in a rural community in Hokkaido, Japan. METHODS: Cranial CT was performed between 1991 and 1993, graded for ventricular enlargement, sulcal enlargement, white matter change, and small infarction. Functional status was reassessed in 1998 in each participant. Multiple logistic regression analysis was performed to estimate the association of CT changes in the ageing brain with development of functional dependence over six years. RESULTS: Functional dependence was found in 19 residents at the second survey. After adjusting for age, sex, medical conditions, and cognitive functioning, small infarction and ventricular enlargement were significantly associated with development of functional dependence (adjusted odds ratio = 9.27 and 4.62). CONCLUSIONS: After controlling for age, the age-related changes on cranial CT have significant association on development of functional dependence.