Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 4 de 4
Filter
Add more filters










Database
Language
Publication year range
1.
Izv Akad Nauk Ser Biol ; (5): 524-31, 2011.
Article in Russian | MEDLINE | ID: mdl-22117419

ABSTRACT

Arginase activity in erythrocytes is higher in patients with arterial hypertension and atherosclerosis as compared with healthy people. Therapy with either lisinopril alone or in combination with simvastatin for 3-6 months causes a decrease in the arginase activity to the control level. Both the monotherapy and the combination therapy increased the concentrations of NO2(-), NO3(-), and total NOO2(-) + NO3(-)in the plasma of hypertensive patients. The NO2(-) + NO3(-) concentration in erythrocytes decreases in hypertensive patients but is completely restored after therapy with lisinopril alone or in combination with simvastatin. Thus, lisinopril and lisinopril plus simvastatin display a pronounced and equal normalizing effect on arginase activity in human erythrocytes, which is elevated in hypertension, as well as on the endothelial nitric oxide synthase activity, which is decreased in hypertension.


Subject(s)
Arginase/drug effects , Lisinopril/pharmacology , Nitrates/blood , Nitrites/blood , Simvastatin/pharmacology , Adult , Aged , Arteriosclerosis/drug therapy , Drug Combinations , Erythrocytes/drug effects , Erythrocytes/enzymology , Female , Humans , Hypertension/drug therapy , Male , Middle Aged , Nitric Oxide Synthase Type III/drug effects
2.
Biofizika ; 47(1): 130-4, 2002.
Article in Russian | MEDLINE | ID: mdl-11855283

ABSTRACT

It was shown that plantlets of wheat (Triticum vulgare) are capable of generating negative aeroions during the electrization of soil by high-voltage impulses. Soil electrization was carried out either from the moment of planting of seeds or from the appearance of the first seedlings. The concentration of negative ions was measured in the air at a distance of 50 cm from plants. In both variants, similar growth-related changes in the concentration of negative ions were observed. The generation of negative ions began on day 6 after the planting of seeds and reached a concentration of 380 x 10(3) ion/cm3. During the next three days, this level remained unchanged. On day 10, the generation of negative aeroions increased abruptly; on days 10-14, it was twofold as high as on days 7-9. The level of generation of negative aeroions by plants stimulated from the moment of appearance of plantlets was 5-8% higher than by plants stimulated from the moment of planting. The intensity of generation of negative aeroions upon additional illumination and in full darkness remained unchanged.


Subject(s)
Electricity , Ions , Soil , Triticum/physiology
SELECTION OF CITATIONS
SEARCH DETAIL
...