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1.
Arkh Patol ; 66(1): 44-50, 2004.
Article in Russian | MEDLINE | ID: mdl-15055112

ABSTRACT

The information concerning general pathological changes in hair cells of the spiral organ is reviewed. The conditions for the onset, morphological picture of dystrophy, necrosis, apoptosis typical for hair cells in respect to structural and functional features of the sensory epithelium of the spiral organ are outlined. Nonspecific morphological changes of the spiral organ neuroepithelium after the action of damaging agents of different origin (such ototoxic drugs as aminoglycoside antibiotics and others, intensive acoustic impacts, ageing of the acoustic analyzer) are emphasized.


Subject(s)
Apoptosis , Organ of Corti/pathology , Animals , Hair Cells, Auditory/pathology , Humans , Necrosis
3.
Vestn Otorinolaringol ; (6): 13-4, 1998.
Article in Russian | MEDLINE | ID: mdl-10081392

ABSTRACT

Diagnostic sensitivity was compared for two binaural methods of "sensitized" speech audiometry--alternating speech audiometry (ASA) and Dichotic. A total of 35 patients were examined having neurosensory hypoacusis resultant from cerebrovascular atherosclerosis and chronic insufficiency of cerebral circulation. ASA indicated defects of the central parts of the acoustic analyzer in 80% of the examinees. The results of the two methods were similar in 85.7% of the patients. The diotic and dichotic alternating speech tests can be used separately and in combination in diagnosis of central acoustic disturbances, of vascular genesis, in particular.


Subject(s)
Audiometry, Speech , Auditory Perception/physiology , Hearing Loss, Sensorineural/diagnosis , Neural Analyzers/physiology , Aged , Aged, 80 and over , Audiometry, Speech/methods , Cerebrovascular Circulation , Female , Hearing Loss, Sensorineural/etiology , Humans , Intracranial Arteriosclerosis/complications , Male , Middle Aged
4.
Vestn Otorinolaringol ; (2): 18-21, 1990.
Article in Russian | MEDLINE | ID: mdl-2360301

ABSTRACT

Hearing thresholds at speech frequencies in children with neurosensory hypoacusis were measured by three methods: orientation reflex (OR), wink reflex (WR) and brain acoustic evoked responses (BERA). Hearing thresholds measured by recording OR and WR were compared in 115 children (232 comparisons) and were found to coincide in about 92% of cases. Hearing thresholds at speech frequencies were measured by recording OR, WR and BERA in 55 children (103 comparisons) and were found to coincide in about 70% of cases. The discrepancy in the thresholds, especially when measured by means of BERA and WR, was seen mainly in the children who suffered from neurosensory hypoacusis and other CNS disorders (oligophrenia, residual manifestations of birth cerebral palsy with mental retardation, symptoms of sensory alalia). It is concluded that the method of recording WR allows a sufficiently accurate measurement of hearing thresholds. However, a comprehensive examination should be performed using all three methods to reveal concomitant diseases.


Subject(s)
Audiometry, Evoked Response , Blinking/physiology , Hearing Loss, Sensorineural/physiopathology , Hearing/physiology , Child , Child, Preschool , Female , Humans , Male
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