ABSTRACT
The article "Three new ent-abietane diterpenoids from the roots of Euphorbia fischeriana and their cytotoxicity in human tumor cell lines", written by Minghui Li, Fang He, Yuan Zhou, Meigui Wang, Pingde Tao, Qingmei Tu, Guanghui Lv, Xintao Chen, was originally published electronically on the publisher's internet portal (currently SpringerLink) on 17 April 2019 with open access. With the author(s)' decision to step back from Open Choice, the copyright of the article changed on 4 September 2020 to © The Pharmaceutical Society of Korea 2020 and the article is forthwith distributed under the terms of copyright. The original article has been corrected.
ABSTRACT
Three new ent-abietane diterpenoids, termed fischerianoids A-C (1-3), were isolated and identified from the ethyl acetate extracts of roots of the medicinally valuable plant Euphorbia fischeriana. The planar and relative structures of 1-3 were established via high-resolution electrospray ionisation mass spectrometry and one- and two-dimensional nuclear magnetic resonance spectroscopic analyses, and the absolute configuration of 1 was further established via X-ray crystallography experiment. Compounds 1-3 showed selective inhibitory potency against certain human tumor cell lines with IC50 values ranging from 8.50 ± 0.13 to 35.52 ± 0.08 µM.
