1.
Dermatol Ther
; 32(4): e12991, 2019 07.
Article
in English
| MEDLINE
| ID: mdl-31172613
ABSTRACT
CLAPO syndrome (Capillary vascular malformation of the lower lip, Lymphatic malformations of the head and neck, Asymmetry and Partial or generalized Overgrowth) is a nonfrequent pathology. This syndrome is characterized by the capillary malformation (CM) of the lower lip, a very important clinical sign when diagnosing CLAPO. The aim of our report is to demonstrate that rapamycin could be a reliable and safe targeted therapy in lymphatic malformations (LMs). This drug is useful in reducing the LM's size before final surgical treatment. The clinical and radiological evolution of a patient with CLAPO syndrome is reported in this article, before and after the treatment with rapamycin.
Subject(s)
Arteriovenous Malformations/drug therapy , Immunosuppressive Agents/administration & dosage , Lymphatic Diseases/drug therapy , Sirolimus/administration & dosage , Administration, Oral , Arteriovenous Malformations/physiopathology , Humans , Immunosuppressive Agents/adverse effects , Infant, Newborn , Lymphatic Diseases/physiopathology , Male , Sirolimus/adverse effects , Treatment Outcome
2.
J Pediatr Urol
; 8(3): 313, 2012 Jun.
Article
in English
| MEDLINE
| ID: mdl-21481642
3.
J Pediatr Surg
; 43(10): 1949; author reply 1949-50, 2008 Oct.
Article
in English
| MEDLINE
| ID: mdl-18926241