Subject(s)
Anti-Arrhythmia Agents/therapeutic use , Arrhythmia, Sinus/drug therapy , Arrhythmia, Sinus/physiopathology , Dinoprostone/therapeutic use , Sinoatrial Node/physiopathology , Adolescent , Adult , Aged , Anti-Arrhythmia Agents/pharmacology , Arrhythmia, Sinus/diagnosis , Dinoprostone/pharmacology , Echocardiography, Transesophageal , Female , Heart Rate/drug effects , Heart Rate/physiology , Humans , Male , Middle AgedABSTRACT
Cross-over trial studied comparative effectiveness and tolerance of allapinine, rhythmonorm and isoptine in patients with paroxysmal supraventricular tachycardia (PSVT). Treatment effects did not differ much. Analysis of the preventive efficiency of the above drugs with reference to PSVT form has demonstrated that in paroxysmal atrioventricular reciprocal tachycardia the highest activity was shown by isoptine and rhythmonorm, in paroxysmal orthodromic reciprocal tachycardia--by rhythmonorm and allapinin. In long-term therapy, a preventive effects of allapinin, rhythmonorm and isoptine achieved at short-term course therapy persisted in 90.9, 95.6 and 81.5% patients, respectively. All the above drugs cause moderate inhibition of atrioventricular and intraventricular conduction. Isoptin had the best tolerance.
Subject(s)
Aconitine/analogs & derivatives , Aconitine/therapeutic use , Anti-Arrhythmia Agents/therapeutic use , Tachycardia, Paroxysmal/drug therapy , Tachycardia, Supraventricular/drug therapy , Verapamil/therapeutic use , Adolescent , Adult , Aged , Cross-Over Studies , Female , Humans , Male , Middle Aged , Tachycardia, Paroxysmal/complications , Tachycardia, Supraventricular/complicationsSubject(s)
Disability Evaluation , Hypertension/diagnosis , Adult , Age Factors , Female , Humans , Hypertension/economics , Hypertension/epidemiology , Kazakhstan , Male , Middle Aged , Sex Factors , Urban Population , WorkABSTRACT
The activity of some organ specific enzymes of the liver subcellular structures in the blood serum was examined in 56 patients with cardiogenic shock. The correlation between the gravity of clinical signs of cardiogenic shock and blood enzyme degree was revealed. It was concluded that biochemical criteria could be used in the diagnosis of irreversible changes in the liver in cardiogenic shock.
Subject(s)
Liver/enzymology , Myocardial Infarction/enzymology , Shock, Cardiogenic/enzymology , Acid Phosphatase/blood , Aged , Cholinesterases/blood , Female , Fructose-Bisphosphate Aldolase/blood , Glutamate Dehydrogenase/blood , Humans , Male , Middle Aged , Myocardial Infarction/complications , Organ Specificity , Shock, Cardiogenic/etiologySubject(s)
Liver/enzymology , Myocardial Infarction/metabolism , Vitamin E/analogs & derivatives , alpha-Tocopherol/analogs & derivatives , Acid Phosphatase/metabolism , Adult , Aged , Cholinesterases/metabolism , Female , Fructose-Bisphosphate Aldolase/metabolism , Glutamate Dehydrogenase/metabolism , Humans , Lipid Peroxides/antagonists & inhibitors , Lipid Peroxides/biosynthesis , Male , Middle Aged , Myocardial Infarction/therapy , Organ Specificity , Tocopherols , Vitamin E/therapeutic useSubject(s)
Ductus Arteriosus, Patent/diagnosis , Adolescent , Adult , Child , Child, Preschool , Echocardiography , Female , Humans , MaleSubject(s)
Echocardiography , Mitral Valve Stenosis/diagnosis , Mitral Valve/surgery , Adolescent , Adult , Female , Follow-Up Studies , Humans , Male , Middle Aged , Mitral Valve Stenosis/surgeryABSTRACT
The rationale of undertaing operative interventions in pregnant women with mitral stenosis of the III and IV stages is analyzed. On the basis of his investigations the author thinks that in women with severe mitral stenosis of the II and IV stages and with the gestation term of up to 30 weeks mitral commissurotomy is indicated. In patients at these stages of the disease and with full-term pregnancy laparotomy may be performed when there is no pulmonary edema and no risk of its development. Simultaneous mitral commissurotomy and cesarian section are indicated in women with mitral stenosis of the III and IV stages and full-term pregnancy in cases of already existing pulmonary edema or when there is a danger of its development.
Subject(s)
Mitral Valve Stenosis/surgery , Pregnancy Complications, Cardiovascular/surgery , Adolescent , Adult , Cesarean Section , Female , Humans , Methods , Mitral Valve/surgery , Pregnancy , Pregnancy Trimester, Third , Time FactorsABSTRACT
The purpose of the work was to ascertain the degree of reliability achievable by an indirect measurement of pressure in the pulmonary artery in pregnant women with congenital and acquired heart diseases. To determine the pressure in the pulmonary artery by the indirect method electro-phonocardiograms and a phlebogram from the jugular vein were recorded simultaneously. The pressure in the pulmonary artery was measured with reference to the duration of the isometric relaxation period of the right ventricle, estimated from the distance between the pulmonary component of the II sound and the beginning of the diastolic fall on the phlebogram. By registering the duration of this period and the heart rate the systolic pressure in the pulmonary artery was found from the nomogram. A total of 55 patients, including 19 pregnant women, were examined. The pressure levels calculated by the indirect method were contrasted against the results obtained through catheterization of the cardiac cavities, or during surgery--by direct puncturing. Investigations have shown a high degree of reliability of the estimated pressure levels in the pulmonary artery of patients with congenital and acquired cardiac defects. The indirect method of measuring the pulmonary artery pressure is simple, quite safe and accurate. It allows one to ascertain the extent of pulmonary hypertension in pregnant women irrespective of the type of the defect, the age and the intensity of the pulmonary hypertension.
