ABSTRACT
A new antiseptic contrast material, composed of sodium diatrizoate-meglumine diatrizoate and PVP-iodine solutions, was prepared and tested for operative cholangiography. It was tested in vitro, and in vivo in dogs and displayed satisfactory contrast radiologic features, and strong and rapid bactericidal action without detectable side effects. It seems to be promising in reducing the risk of bacterial spread during cholangiography.
Subject(s)
Anti-Infective Agents, Local/therapeutic use , Cholangiography/methods , Contrast Media , Animals , Bacterial Infections/prevention & control , Cholangiography/adverse effects , Diatrizoate , Diatrizoate Meglumine , Dogs , Evaluation Studies as Topic , Female , In Vitro Techniques , Male , Povidone-IodineABSTRACT
A new antiseptic contrast material, composed of sodium diatrizoate-meglumine diatrizoate and PVP-iodine solution, was prepared and tested for retrograde cystography. It was tested in vitro and in dogs, showed satisfactory radiological features and rapid wide bactericidal action without detectable side effects. Septic complications following radiological demonstration of the urinary tract may be reduced.