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1.
PLoS One ; 18(2): e0279105, 2023.
Article in English | MEDLINE | ID: mdl-36795702

ABSTRACT

OBJECTIVE: During certain phases of the COVID-19 pandemic, a decrease was observed in emergency department (ED) utilization. Although this phenomenon has been thoroughly characterized for the first wave (FW), second wave (SW) studies are limited. We examined the changes in ED utilization between the FW and SW, compared to 2019 reference periods. STUDY DESIGN AND METHODS: We performed a retrospective analysis of ED utilization in 3 Dutch hospitals in 2020. The FW and SW (March-June and September-December, respectively) were compared to the reference periods in 2019. ED visits were labeled as (non-)COVID-suspected. RESULTS: During the FW and SW ED visits decreased by 20.3% and 15.3%, respectively, when compared to reference periods in 2019. During both waves high urgency visits significantly increased with 3.1% and 2.1%, and admission rates (ARs) increased with 5.0% and 10.4%. Trauma related visits decreased by 5.2% and 3.4%. During the SW we observed less COVID-related visits compared to the FW (4,407 vs 3,102 patients). COVID-related visits were significantly more often in higher need of urgent care and ARs were at least 24.0% higher compared to non-COVID visits. CONCLUSION: During both COVID-19 waves, ED visits were significantly reduced. ED patients were more often triaged as high urgent, the ED length of stay was longer and ARs were increased compared to the reference period in 2019, reflecting a high burden on ED resources. During the FW, the reduction in ED visits was most pronounced. Here, ARs were also higher and patient were more often triaged as high urgency. These findings stress the need to gain better insight into the motives of patients to delay or avoid emergency care during pandemics, as well as to better prepare EDs for future outbreaks.


Subject(s)
COVID-19 , Humans , Retrospective Studies , COVID-19/epidemiology , Netherlands/epidemiology , Pandemics , Emergency Service, Hospital , Hospitals
2.
J Gastrointest Surg ; 26(7): 1373-1387, 2022 07.
Article in English | MEDLINE | ID: mdl-35488019

ABSTRACT

PURPOSE: There is a lack of prospective studies evaluating the effects of body composition on postoperative complications after gastrectomy in a Western population with predominantly advanced gastric cancer. METHODS: This is a prospective side study of the LOGICA trial, a multicenter randomized trial on laparoscopic versus open gastrectomy for gastric cancer. Trial patients who received preoperative chemotherapy followed by gastrectomy with an available preoperative restaging abdominal computed tomography (CT) scan were included. The CT scan was used to calculate the mass (M) and radiation attenuation (RA) of skeletal muscle (SM), visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT). These variables were expressed as Z-scores, depicting how many standard deviations each patient's CT value differs from the sex-specific study sample mean. Primary outcome was the association of each Z-score with the occurrence of a major postoperative complication (Clavien-Dindo grade ≥ 3b). RESULTS: From 2015 to 2018, a total of 112 patients were included. A major postoperative complication occurred in 9 patients (8%). A high SM-M Z-score was associated with a lower risk of major postoperative complications (RR 0.47, 95% CI 0.28-0.78, p = 0.004). Furthermore, high VAT-RA Z-scores and SAT-RA Z-scores were associated with a higher risk of major postoperative complications (RR 2.82, 95% CI 1.52-5.23, p = 0.001 and RR 1.95, 95% CI 1.14-3.34, p = 0.015, respectively). VAT-M, SAT-M, and SM-RA Z-scores showed no significant associations. CONCLUSION: Preoperative low skeletal muscle mass and high visceral and subcutaneous adipose tissue radiation attenuation (indicating fat depleted of triglycerides) were associated with a higher risk of developing a major postoperative complication in patients treated with preoperative chemotherapy followed by gastrectomy.


Subject(s)
Stomach Neoplasms , Body Composition , Female , Gastrectomy/adverse effects , Humans , Male , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Postoperative Complications/surgery , Prospective Studies , Retrospective Studies , Stomach Neoplasms/surgery
3.
Int J Colorectal Dis ; 36(7): 1535-1542, 2021 Jul.
Article in English | MEDLINE | ID: mdl-33977333

ABSTRACT

PURPOSE: Despite the enhanced recovery after surgery (ERAS) protocol, length of stay (LOS) after colorectal surgery varies considerably. The majority of longer admissions is often not medically necessary. We aimed to investigate possible reduction of LOS by perioperative education with an expected discharge date (EDD). METHODS: This single-centre retrospective study included 578 patients who underwent surgery for colorectal cancer in 2016 with standard care (ERAS) and in 2018 with the addition of EDD education program (ERAS+). A comparison was made of a 1-year period prior to and following the implementation of EDD. The EDD was discussed at the outpatient clinic, preoperatively and during admission (with both the patient and family members daily). Standard EDD varied between 3 and 5 days depending on the resection type. Primary outcome was LOS; secondary outcomes were readmission, serious complications and 90-day mortality. RESULTS: Patients in ERAS+ (n = 242) had a shorter median LOS (4.0 vs. 5.0, p < 0.001) compared to patients in the regular ERAS group (n = 336). Fewer patients of ERAS+ experienced postoperative complications (71 (29.3%) vs. 198 (58.9%), p < 0.001). No difference was found in the number of readmissions (23 (9.5%) vs. 34 (10.1%), p = 0.807), reinterventions (25 (10.3%) vs. 30 (8.9%), p = 0.571) or mortality (5 (2.1%) vs. 9 (2.7%), p = 0.261) between the two groups. CONCLUSION: It is possible to reduce LOS within the ERAS program, by better perioperative education and expectation management of patients with use of an EDD. This program ensures better understanding, faster discharge and lower costs for the hospital without added risk of readmissions or complications.


Subject(s)
Colorectal Surgery , Enhanced Recovery After Surgery , Colorectal Surgery/adverse effects , Humans , Length of Stay , Patient Discharge , Patient Education as Topic , Patient Readmission , Perioperative Care , Postoperative Complications/etiology , Retrospective Studies
4.
Ned Tijdschr Geneeskd ; 1632018 12 05.
Article in Dutch | MEDLINE | ID: mdl-30570944

ABSTRACT

BACKGROUND: A gallstone ileus is a complication of cholelithiasis that is difficult to recognise. Morbidity and mortality are both high. Treatment often consists of surgical removal of the stone. There is limited literature available about less invasive therapies such as extracorporeal shock-wave lithotripsy (ESWL). CASE DESCRIPTION: A 72-year-old man with severe abdominal pain reported to the accident and emergency department. A blockage at the level of the sigmoid colon was visible on the CT scan, with concurrent diverticular stenosis. During a multidisciplinary consultation we decided upon treatment with ESWL. The treatment was successful, and the patient left the hospital in a good condition. CONCLUSION: The most common surgical operation for a gallstone ileus is extraction through an enterotomy. The minimally invasive ESWL technique, however, seems to be a good alternative. To date, there have only been case study reports of this in the literature.


Subject(s)
Extracorporeal Shockwave Therapy , Gallstones/therapy , Ileum/pathology , Ileus/therapy , Lithotripsy , Abdominal Pain/etiology , Abdominal Pain/surgery , Aged , Cholelithiasis/complications , Enterostomy , Gallstones/complications , Gallstones/surgery , Humans , Ileum/surgery , Ileus/etiology , Ileus/surgery , Intestinal Obstruction/etiology , Intestinal Obstruction/surgery , Intestinal Obstruction/therapy , Male , Tomography, X-Ray Computed/methods
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