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1.
Nanomaterials (Basel) ; 11(2)2021 Feb 11.
Article in English | MEDLINE | ID: mdl-33670119

ABSTRACT

Efficient application of carbon nanotubes (CNTs) in nano-devices and nano-materials requires comprehensive understanding of their mechanical properties. As observations suggest size dependent behaviour, non-classical theories preserving the memory of body's internal structure via additional material parameters offer great potential when a continuum modelling is to be preferred. In the present study, micropolar theory of elasticity is adopted due to its peculiar character allowing for incorporation of scale effects through additional kinematic descriptors and work-conjugated stress measures. An optimisation approach is presented to provide unified material parameters for two specific class of single-walled carbon nanotubes (e.g., armchair and zigzag) by minimizing the difference between the apparent shear modulus obtained from molecular dynamics (MD) simulation and micropolar beam model considering both solid and tubular cross-sections. The results clearly reveal that micropolar theory is more suitable compared to internally constraint couple stress theory, due to the essentiality of having skew-symmetric stress and strain measures, as well as to the classical local theory (Cauchy of Grade 1), which cannot accounts for scale effects. To the best of authors' knowledge, this is the first time that unified material parameters of CNTs are derived through a combined MD-micropolar continuum theory.

2.
J Adv Prosthodont ; 9(4): 308-314, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28874999

ABSTRACT

PURPOSE: The purpose of this study was to analyze the retention force changes and wear behaviours of double-crown systems over long-term use. MATERIALS AND METHODS: Ten groups, each consisting of six samples, were evaluated. Specifically, casting gold alloy primary crown - casting gold alloy secondary crown (AA), laser sintering primary crown - laser sintering secondary crown (LL), casting Cr alloy primary crown - casting Cr alloy secondary crown, (CC) zirconia primary crown - electroformed secondary crown (ZA), and CAD/CAM titanium alloy primary crown - CAD/CAM titanium alloy secondary crown (TT) groups were evaluated at cone angles of 4° and 6°. The samples were subjected to 5,000 insertion-separation cycles in artificial saliva, and the retention forces were measured every 500 cycles. The wear levels were analyzed via SEM at the beginning and end of the 5,000 cycles. RESULTS: In all samples, the retention forces increased when the conus angle decreased. The highest initial and final retention force values were found in the LL-4° group (32.89 N-32.65 N), and the lowest retention force values were found in the ZA6° group (5.41 N-6.27 N). The ZA groups' samples showed the least change in the retention force, and no wear was observed. In the other groups, wear was observed mostly in the primary crowns. CONCLUSION: More predictable, clinically relevant, and less excursive retention forces can be observed in the ZA groups. The retention force values of the LL groups were statically similar to those of the other groups, except the ZA groups.

3.
J Orthop Sci ; 21(5): 640-6, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27292115

ABSTRACT

BACKGROUND: Various types of shortening osteotomies and prosthesis are used for femoral reconstruction in total hip arthroplasty of the high hip dislocation. This biomechanical study investigates whether step-cut osteotomies result in better stability than oblique osteotomies and cylindrical femoral stems enhance stability of the osteotomy more than conical stems, and which osteotomy and prosthesis type maintain the stability better after cyclical loading. METHODS: Oblique and step-cut shortening osteotomies were compared under axial and rotational forces, using synthetic femur models and conical or cylindrical femoral prostheses. The models underwent cyclic loading for 10,000 cycles at 3 Hz (100-1000 N axial bending or 0.5-10 Nm torque). After the completion of cyclic loading, the models were loaded until failure. Stiffness values before and after cyclical loading, and failure loads were the outcome parameters. Relative displacements at the osteotomy sites were also measured using 3-Dimensions Digital Imaging Correlation System. RESULTS: The mean failure load was significantly higher in conical prosthesis groups under axial forces. In torsion tests, the mean stiffness of conical prosthesis groups after cyclical loading was higher in oblique osteotomies. The other parameters were similar between the groups. CONCLUSIONS: According to the results of the study, although some individual statistically significant parameters were obtained, step-cut osteotomies, which are technically challenging procedures, were not found biomechanically superior to oblique osteotomies, with neither conical nor cylindrical prostheses.


Subject(s)
Arthroplasty, Replacement, Hip/methods , Femur Head/surgery , Hip Dislocation/surgery , Osteotomy/methods , Stress, Mechanical , Biomechanical Phenomena , Hip Prosthesis , Humans , Models, Anatomic , Sensitivity and Specificity , Weight-Bearing
4.
Plast Reconstr Surg ; 137(6): 1784-1791, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27219234

ABSTRACT

BACKGROUND: The harvesting of septal cartilage following mucoperichondrial flap elevation has almost become a standard step in rhinoplasty. However, the strength of the remaining septum has not yet been evaluated. In the current experimental study of a rabbit rhinoplasty model, the remaining septum following a graft harvest was analyzed both biomechanically and pathologically. METHODS: Forty New Zealand rabbits were classified into four equal groups. Group 1 consisted of the animals in which unilateral elevation of the mucoperichondrial flaps was undertaken before the graft harvest, group 2 consisted of the animals in which bilateral elevation was undertaken, group 3 included the animals where the septum was exposed and left untouched after a bilateral mucosal flap elevation, and group 4 was designated as the control group. Specimens were analyzed under light microscopy for multiple parameters. Biomechanical analyses were performed with a universal testing device at the Department of Engineering, Biomechanical Laboratories, Istanbul Technical University. RESULTS: Biomechanical analysis in terms of maximum tension revealed significant results among the groups (p = 0.008). Although insignificant results were observed overall using a pathologic analysis, the amount of chondrocytes was lower in group 2 than in group 1 (p = 0.099). The amounts of matrix collagen (p = 0.184) and fibrosis were (p = 0.749) higher in group 2 than in group 1. CONCLUSIONS: From these data, the authors conclude that mucoperichondrium integrity plays a crucial role in the biomechanical strength of the septum. More sophisticated studies with further pathologic analysis are required to determine the exact mechanism of strength loss observed with mucoperichondrial flap elevation.


Subject(s)
Chondrocytes/transplantation , Nasal Cartilages/surgery , Nasal Septum/surgery , Prostheses and Implants , Rhinoplasty/methods , Surgical Flaps , Animals , Female , Male , Rabbits
5.
Clin Orthop Relat Res ; 473(10): 3190-6, 2015 Oct.
Article in English | MEDLINE | ID: mdl-25981711

ABSTRACT

BACKGROUND: Infection after open fractures is a common complication. Treatment options for infections developed after intramedullary nailing surgery remain a topic of controversy. We therefore used a rat fracture model to evaluate the effects of infection on osseous union when the implant was maintained. QUESTIONS/PURPOSES: In a rat model, (1) does infection alter callus strength; (2) does infection alter the radiographic appearance of callus; and (3) does infection alter the histological properties of callus? METHODS: An open femoral fracture was created and fixed with an intramedullary Kirschner wire in 72 adult male Sprague-Dawley rats, which were divided into two study groups. In the infection group, the fracture site was contaminated with Staphylococcus aureus (36 animals), whereas in the control group, there was no bacterial contamination (36 animals). No antibiotics were used either for prophylaxis or for treatment. We performed biomechanical (maximum torque causing failure and stiffness), radiographic (Lane and Sandhu scoring for callus formation), and histologic (scoring for callus maturity) assessments at 3 and 6 weeks. The number of bacteria colonies on the femur, wire, and soft tissue inside knee were compared to validate that we successfully created an infection model. The number of bacteria colonies in the soft tissue inside the knee was higher in the infection group after 6 weeks than after the third week, demonstrating the presence of locally aggressive infection. RESULTS: Infection decreased callus strength at 6 weeks. Torque to failure (299.07 ± 65.53 Nmm versus 107.20 ± 88.81, mean difference with 95% confidence interval, 192 [43-340]; p = 0.007) and stiffness at 6 weeks (11.28 ± 2.67 Nmm versus 2.03 ± 1.68, mean difference with 95% confidence interval, 9 [3-16]; p = 0.004) both were greater in the control group than in the group with infection. Radiographic analysis at 6 weeks demonstrated the fracture line was less distinct (Lane and Sandhu score of 2-3) in the infection group and complete union was observed (Lane and Sandhu score of 3-4) in the control group (p = 0.001). Semiquantitative histology scores were not different between the noninfected controls and the rats with infection (score 10 versus 9). CONCLUSIONS: Retaining an implant in the presence of an underlying infection without antibiotic treatment leads to weaker callus and impedes callus maturation compared with noninfected controls in a rat model. Future studies might evaluate whether antibiotic treatment would modify this result. CLINICAL RELEVANCE: This model sets the stage for further investigations that might study the influence of different interventions on fracture healing in implant-associated osteomyelitis. Future observational studies might also evaluate the histological properties of callus in patients with osteomyelitis.


Subject(s)
Bone Nails/adverse effects , Bony Callus , Femoral Fractures/surgery , Fracture Healing , Prosthesis-Related Infections/etiology , Animals , Bony Callus/diagnostic imaging , Bony Callus/pathology , Bony Callus/physiopathology , Disease Models, Animal , Male , Models, Animal , Orthopedic Procedures , Radiography , Rats, Sprague-Dawley
6.
J Biomech ; 47(12): 2883-90, 2014 Sep 22.
Article in English | MEDLINE | ID: mdl-25110168

ABSTRACT

Due to its significance in tooth movement, the stress/deformation field of periodontium and the alveolar bone remodeling process, periodontal ligament (PDL) cannot be excluded from the studies investigating dental biomechanics regarding its excessive deformability. Therefore, many analytical and numerical researches are carried out to simulate its response and to create a constitutive model via experiments intending to discover the material properties of PDL. The aim of this study is to formulate a user specified contact model that can be used in conjunction with finite element (FE) software and reflects PDL's influence on neighboring structures based on the currently available information, without requiring an actual volumetric finite element mesh of ligament. The results show good agreement with available experimental tooth mobility data. Smooth stress fields are obtained on the tooth root and alveolar bone, which is a significant aspect in bone-remodeling studies. The advantage of simulating PDL as a contact model at the interface of tooth root and the alveolar process instead of a solid-meshed FE model with poor geometric morphology and/or very dense mesh is expected to save pre/post-processing workforce, to increase the accuracy and to contribute to the smoothness of interface stress distributions.


Subject(s)
Alveolar Process/physiology , Models, Biological , Periodontal Ligament/physiology , Tooth Root/physiology , Biomechanical Phenomena , Bone Remodeling/physiology , Computer Simulation , Finite Element Analysis , Humans , Nonlinear Dynamics , Reproducibility of Results , Stress, Mechanical , Tooth Mobility/physiopathology
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