ABSTRACT
In this study the in vitro susceptibility of 1,009 Gram-positive strains isolated from 4,505 positive urocultures was evaluated towards the following chemotherapeutic agents: oxacillin, ampicillin, amoxicillin + clavulanic acid, imipenem, cefalotin, cefotaxime, amikacin, gentamicin, ciprofloxacin, pefloxacin, clindamycin, erythromycin, vancomycin, rifampicin, tetracycline and chloramphenicol. The results indicate that vancomycin is the most active antibiotic against all the strains, including enterococci often involved in serious infections caused by invasive techniques.
Subject(s)
Anti-Bacterial Agents/pharmacology , Gram-Positive Bacteria/drug effects , Gram-Positive Bacterial Infections/microbiology , Urinary Tract Infections/microbiology , Ambulatory Care , Cross Infection/microbiology , Drug Resistance, Microbial , Gram-Positive Bacteria/isolation & purification , Hospitalization , Humans , Microbial Sensitivity TestsABSTRACT
The in vitro activity of imipenem against 3,496 Gram-negative strains isolated from 4,505 positive urocultures was determined. The effectiveness of imipenem was then compared with that of ampicillin, amoxycillin + clavulanic acid, ticarcillin, piperacillin, aztreonam, cefalotin , ceftazidime, cefoxitin, cefotaxime, norfloxacin, ciprofloxacin, amikacin, gentamicin, tobramycin, trimethoprim + sulfamethoxazole. Imipenem was active against all isolates, including Pseudomonas spp. known to account for a large portion of nosocomial infections and resistance to antibacterial drugs.