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1.
Acta Ophthalmol Scand ; 81(5): 530-2, 2003 Oct.
Article in English | MEDLINE | ID: mdl-14510804

ABSTRACT

CONTEXT: A 32-year-old woman was scheduled for myopic laser in situ keratomileusis (LASIK) because of myopia and anisometropia caused by retinal detachment surgery. CASE REPORT: During surgery, a sudden malfunction of the microkeratome during the forward pass was experienced. It was not possible to reverse the blade manually along the suction ring. Moreover, disconnecting the suction from the control unit did not help at first, because the suction ring was firmly attached to the ocular surface. However, detaching the suction line from the control unit aborted the vacuum and allowed the surgeon to turn the whole microkeratome backwards, mimicking the normal blade movement. Finally, an almost normal flap was observed, and the operation was successfully completed. Afterwards, the wire to the electromotor of the microkeratome was found to be broken and subsequently replaced. CONCLUSION: This type of unforeseen microkeratome malfunction may result in serious flap or other complications.


Subject(s)
Anisometropia/surgery , Keratomileusis, Laser In Situ/adverse effects , Keratomileusis, Laser In Situ/instrumentation , Myopia/surgery , Adult , Anisometropia/etiology , Corneal Topography , Electricity , Equipment Failure , Female , Humans , Myopia/etiology , Ophthalmologic Surgical Procedures/adverse effects , Postoperative Period , Preoperative Care , Retinal Detachment/surgery , Surgical Flaps , Surgical Instruments/adverse effects
3.
Invest Ophthalmol Vis Sci ; 44(6): 2545-9, 2003 Jun.
Article in English | MEDLINE | ID: mdl-12766055

ABSTRACT

PURPOSE: To analyze the in vivo morphology of the different corneal sublayers and corneal nerves in primary Sjögren's syndrome (SS). METHODS: Ten eyes of 10 patients with primary SS and 10 eyes of 10 sex- and age-matched control subjects were investigated. Diagnosis was based on American-European consensus criteria. In vivo confocal microscopy with through-focusing was used to investigate corneal morphology and to measure corneal sublayer thickness. RESULTS: Epithelial punctate staining with fluorescein was observed in 6 of 10 SS and none of 10 control corneas. In addition, Schirmer I test results were significantly lower in SS. Epithelial thickness did not differ between the SS and control groups. Confocal microscopy revealed patchy alterations or irregularities in surface epithelial cells in 6 of 10 SS corneas, whereas the basal epithelium appeared normal in all corneas. Average corneal thickness was lower in the SS group (515.9 +/- 22.0 micro m) than in the control (547.4 +/- 42.0 micro m; P = 0.050, t-test). Accordingly, the mean intraocular pressure was lower in the SS group (13.9 +/- 2.1 mm Hg) than in the control (16.7 +/- 2.9 mm Hg; P = 0.022). The subbasal nerve plexus and stromal nerve fiber bundles were present in all corneas. No difference was noted in nerve density. However, in 4 of 10 SS eyes, the subbasal nerve plexus showed structures resembling nerve sprouting, suggesting ongoing active neural growth. None of the control corneas exhibited such features. Signs of anterior keratocyte activation were observed in 5 of 10 SS corneas. CONCLUSIONS: In SS, the corneal surface epithelium was irregular and patchy. Anterior keratocytes frequently showed morphologic features of activation. The subbasal nerve fiber bundles revealed abnormal morphology, and the central corneal thickness was reduced by stromal thinning. The findings confirm epithelial, stromal, and neural abnormalities in the corneas of patients with SS.


Subject(s)
Cornea/innervation , Cranial Nerve Diseases/pathology , Ophthalmic Nerve/pathology , Sjogren's Syndrome/pathology , Adult , Aged , Corneal Stroma/pathology , Epithelium, Corneal/pathology , Female , Fibroblasts/pathology , Humans , Intraocular Pressure , Male , Microscopy, Confocal , Middle Aged
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