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Opt Lett ; 35(5): 631-3, 2010 Mar 01.
Article in English | MEDLINE | ID: mdl-20195301

ABSTRACT

We show that modified Kramers-Kronig relations provide a useful tool to test the validity of the complex refractive index extracted from transmission terahertz spectra of porous matrices containing pharmaceutical materials. The role of scattering of terahertz radiation is qualitatively considered as a reason for the observed discrepancy between experimental data and the values extracted from the inverted complex refractive index. As an example we present an analysis of the terahertz spectra of carbamazepine and lactose alpha-monohydrate.


Subject(s)
Drug Carriers/chemistry , Drug Evaluation, Preclinical/methods , Models, Chemical , Pharmaceutical Preparations/chemistry , Terahertz Spectroscopy/methods , Computer Simulation , Materials Testing , Porosity , Terahertz Radiation
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