ABSTRACT
Polyurethane chemicals are produced by the reaction of isocyanates and they may cause allergic contact dermatitis or precipitate asthma attacks. Contact dermatitis to polyurethane toilet seat has not been reported before. Herein we present a case of allergic contact dermatitis to polyurethane toilet seat.
Subject(s)
Dermatitis, Allergic Contact/diagnosis , Polyurethanes/adverse effects , Toilet Facilities , Adrenal Cortex Hormones/therapeutic use , Child , Dermatitis, Allergic Contact/drug therapy , Female , Humans , Isocyanates , Patch Tests , Treatment OutcomeSubject(s)
Aminoquinolines/administration & dosage , Antineoplastic Agents/administration & dosage , Carcinoma, Basal Cell/drug therapy , Interferon-alpha/administration & dosage , Skin Neoplasms/drug therapy , Administration, Topical , Drug Therapy, Combination , Female , Humans , Imiquimod , Interferon alpha-2 , Middle Aged , Nose Neoplasms/drug therapy , Recombinant ProteinsABSTRACT
Parry-Romberg syndrome (PRS) or progressive hemifacial atrophy is a rare entity characterized by unilateral atrophy of the skin, subcutaneous tissue and sometimes bone and cartilage. Although this syndrome has overlapping features of scleroderma 'en coup de sabre', it shows little or no sclerosis and may affect the entire distribution of the trigeminal nerve including the eye and tongue. As the pathogenesis is unknown, no effective therapy exists. We present here the third case of PRS associated with borreliosis and more interestingly two cases whose progressive course have been stabilized with gel PUVA therapy.
Subject(s)
Borrelia Infections/diagnosis , Facial Hemiatrophy/diagnosis , Adult , Borrelia Infections/complications , Borrelia Infections/drug therapy , Borrelia Infections/pathology , Child , Diagnosis, Differential , Facial Hemiatrophy/complications , Facial Hemiatrophy/drug therapy , Facial Hemiatrophy/pathology , Female , Humans , Male , PUVA Therapy , Scalp/pathology , Tongue/pathologyABSTRACT
Epidermodysplasia verruciformis (EV) is a very rare and chronic disease characterized by a susceptibility to cutaneous infections by a group of phylogenetically related human papillomavirus (HPV) types. We present here a 52-year-old man previously diagnosed and treated as squamous cell carcinoma but also found to have epidermodysplasia verruciformis lesions in association with Bowen's disease. The patient was effectively treated with a combination of interferon therapy (6 million units, twice a week) and topical imiquimod for Bowen's disease (five times a week). We conclude that topical imiquimod is very effective in the treatment of Bowen's disease and may be combined with systemic interferon therapy in rare cases with multiple vivid presentations of HPV infections.
