[Characteristics of regression interrelations between the immune reactions to different staphylococcal strains in chronic inflammatory diseases of the upper respiratory tracts]. / Kharakteristika regressionnykh vzaimosviazei mezhdu immunnymi reaktsiiami k raznym shtammam stafilokokka pri khronicheskikh vospalitel'nykh zabolevaniiakh verkhnikh dykhatel'nykh putei.

Regressive interrelations between antibody titers to 13 staphylococcal museum strains in the blood serum, polypous fluid and saliva of patients with chronic polypous rhinosinusitis and chronic tonsillitis were studied. The presence of sharply defined positive interrelations between antibody titers in the blood serum and polypous fluid of patients with chronic polypous rhinosinusitis with respect to all staphylococcal strains under study and the absence of significant interrelations between antibody titers in the blood serum and saliva of patients with chronic tonsillitis were shown. The problem of the importance of positive or negative interrelations between individual staphylococcal strains is discussed.

[Immunogenicity characteristics of a microorganism population from the pathological foci in chronic inflammatory diseases of the upper respiratory tracts]. / Kharakteristika immunogennosti populiatsii mikroorganizmov patologicheskogo ochaga pri khronicheskikh vospalitel'nykh zabolevaniiakh verkhnikh dykhatel'nykh putei.

The staphylococcal population isolated from the pathologic focus in patients with chronic infectious inflammatory diseases of the upper respiratory tract has been found to be heterogeneous in immune response it induces in the body. The action of immune serum in vivo and in vitro leads rather quickly to quantitative changes in the surface antigenic structures of microbial cells, disappearing in the absence of contact with antibodies. The data obtained in this study indicate that the immunogenicity of microbes easily changes under the influence of immune response, which permits them to evade the immunologic control. It is quite probable that such processes play an essential role in the formation of chronic inflammatory diseases.

[Heterogeneity of agglutinability and antibiotic sensitivity of a population of Staphylococcus aureus isolated from tonsillar lacunae of patients with angina and chronic tonsillitis]. / Neodnorodnost' aggliutinabel'nosti i chuvstvitel'nosti k antibiotikam populiatsii Staphylococcus aureus, vydelennykh iz lakun mindalin u bol'nykh anginoi i khronicheskim tonzillitom.

The study of the staphylococcal microflora of the tonsils in chronic tonsillitis patients revealed a high degree of variability in respect to its sensitivity to different antibiotics and the level of its agglutination by blood serum. The lesser part of the patients showed the presence of staphylococcal clones agglutinated by highly diluted serum and resistant to antibiotics suppressing the main part of the microbial population. The appearance of such clones in the microbial population is supposed to be the reason for the development of antibiotic-resistant population.

[Antibodies to staphylococcal autostrains in polypoid tissue of the human nasal mucosa]. / Antitela k autoshtammam stafilokokka v polipoznoi tkani slizistoi obolochki nosa cheloveka.

The immune response of the body to different clones of nasal staphylococcal population in polypous rhinosinusitis has been studied. The titers of antibodies to different staphylococcal clones were shown to differ considerably. The titers of antibodies to different clones in polypous tissue were found to be higher or lower than the respective titers in the general blood stream. Thus different immunologic conditions for the development of microorganisms could locally appear in the presence of intensive general immune reaction. This seems to be due to differences in the intensity of the production of antibodies to these microorganisms in the lymphoid tissue of the nasal mucosa.