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Chem Commun (Camb) ; 51(19): 4001-4, 2015 Mar 07.
Article in English | MEDLINE | ID: mdl-25622946

ABSTRACT

The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into ß-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.


Subject(s)
Oligopeptides/chemistry , Peptidomimetics/chemistry , Photochemical Processes , Acetic Acid/chemistry , Amino Acid Sequence , Protein Structure, Secondary
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