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Kardiologiia ; 57(4): 58-63, 2017 04.
Article in Russian | MEDLINE | ID: mdl-28762906

ABSTRACT

PURPOSE: to assess efficacy and endotheliotropic properties of short-term addition of meldonium to basic therapy of patients with chronic ischemic heart failure and type 2 diabetes. RESULTS AND CONCLUSION: The study demonstrated the ability of meldonium to significantly improve endothelial function and the state of microcirculatory vascular bed, as well as to influence beneficially heart rate variability.


Subject(s)
Cardiovascular Agents/therapeutic use , Methylhydrazines/therapeutic use , Aged , Cardiovascular Agents/administration & dosage , Chronic Disease , Diabetes Mellitus, Type 2/complications , Female , Heart Failure/complications , Heart Failure/physiopathology , Heart Rate , Humans , Male , Methylhydrazines/administration & dosage , Middle Aged , Myocardial Ischemia/complications
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