[A biological model study of the effect of Aerococcus viridans on pathogenic bacteria]. / Vyvchennia na biolohichnykh modeliakh vplyvu Aerococcus viridans na patohenni bakteriï.

Morphological researches studies showed that the treatment of infected skin wounds with Aerobact quickly eliminated inflammation, promoted regeneration of damaged tissues, that actively stimulated formation of granulations. A decrease of S. aureus virulence which completely or partially loose lethal and necrotic activity is one of the reasons of the observed phenomenon. On the model of S. typhimurium infection the expressed protective action of bacteria of Aerococcus genus was shown; this gives us a good prospect in the expansion of the indications for application of probiotic Aerobact.

[The effect of Aerococcus viridans--the basis of the new therapeutic-prophylactic preparation M-bacterin--on the biological properties of Staphylococcus aureus]. / Vliianie Aerococcus viridans--osnovy novogo lechebno-profilakticheskogo preparata "M-bakterina"--na biologicheskie svoistva Staphylococcus aureus.

Representatives of the normal microflora from genus Aerococcus, in particular strain Aerococcus viridans 167 isolated from breast milk are studied for their effect on biological properties of Staphylococcus aureus in vitro and in vivo. It is established that the number of viable cells of the staphylococcus cultivated in the presence of antagonists in the beef-extract agar decreases progressively with each following passage, the population dying after the seventh-eight passage. Electronograms fix deep changes in the cell ultrastructure. A degree of changes in biological properties depends on the duration of the antagonist action. The results obtained reveal one of the mechanisms of the antagonistic action of aerococci-antagonists producing hydrogen peroxide.