ABSTRACT
Fungi are a promising source of biologically active compounds. Here we publish new data on the antiviral activity of some Agaricomycetes species. We studied the antiviral activity of the total polysaccharide fraction of aqueous extracts from fruiting bodies of eight Agaricomycetes (Hygrophorus agathosmus, H. quelitii, H. speciosus, Clitocybe nebularis, Lactarius deterrimus [two strains], L. porniniae, Russulapelargonia, and R. xerampelina) collected near Dzhazator, Republic of Altay, Russia (Altai Mountains), against a highly pathogenic strain of influenza virus A/Li-petsk/1V/2018 (H1N1 pdm09) (EPI_ISL_332798). All of the studied extracts from the Hygrophorus spp. fruiting bodies showed an antiviral effect, whereas the extracts from Clitocybe, Lactarius, and Russula spp. fruiting bodies did not show such an effect. This is the first report of antiviral activity of extracts from Hygrophorus spp. fruiting bodies.
