ABSTRACT
Intrafamilial transmission of Epstein-Barr virus infections was studied in 35 familial. After infectious mononucleosis was diagnosed in an index child, all siblings were tested for antibodies to EBV. Susceptible children were retested in four to eight weeks. In five families, a concurrent seroconversion was detected in an asymptomatic younger child. Two of 35 seronegative siblings developed clinical IM, confirmed serologically, during the study period. Overall, there evidence of spread in 7 (20%) of the 35 families. We conclude that there is significant intrafamilial transmission of IM. Our findings are compatible with an incubation period of four to six weeks.
Subject(s)
Infectious Mononucleosis/genetics , Adolescent , Adult , Child , Child, Preschool , Family , Female , Humans , Infant , Infectious Mononucleosis/transmission , Male , Middle AgedABSTRACT
Abscess of the salivary glands in the neonatal period is a rare occurrence and almost always involves the parotid gland. A case of suppurative sialadenitis and abscess involving the submandibular gland in a neonate is presented. The diagnosis and management of this uncommon disease are discussed. A review of the literature revealed only three cases of isolated submandibular sialadenitis in neonates.
Subject(s)
Infant, Newborn, Diseases/diagnosis , Salivary Gland Diseases/diagnosis , Sialadenitis/diagnosis , Staphylococcal Infections/diagnosis , Submandibular Gland Diseases/diagnosis , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/therapy , Sialadenitis/therapy , Staphylococcal Infections/therapy , Staphylococcus aureus , Submandibular Gland Diseases/therapyABSTRACT
A 24-week-old girl presented with an acute illness characterised by constipation at 22 weeks, followed a week later by the sudden onset of generalised weakness, poor feeding, and a weak cry. Laboratory examination of her stools confirmed the clinical diagnosis of infant botulism.
