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1.
Scand J Surg ; 105(4): 235-240, 2016 Dec.
Article in English | MEDLINE | ID: mdl-26929281

ABSTRACT

BACKGROUND AND AIMS: According to the heterogeneous results of previous studies, the prevalence of abdominal aortic aneurysm seems high among men with coronary artery disease. The associating risk factors for abdominal aortic aneurysm in this population require clarification. Our objective was to assess the prevalence of non-diagnosed abdominal aortic aneurysms in men with angiographically verified coronary artery disease and to document the associated co-morbidities and risk factors. MATERIAL AND METHODS: Altogether, 407 men with coronary artery disease were screened after invasive coronary angiography in two series at independent centers. Risk factor data were recorded and analyzed. RESULTS AND CONCLUSION: The mean age of the study cohort was 70.0 years (standard deviation: 11.0). The prevalence of previously undiagnosed abdominal aortic aneurysms in the whole screened population of 407 men was 6.1% (n = 25/407). In a multivariate analysis of the whole study population, the only significant risk factors for abdominal aortic aneurysm were age (odds ratio: 1.04, 95% confidence interval: 1.00-1.09) and history of smoking (odds ratio: 3.13, 95% confidence interval: 1.26-7.80). Non-smokers with abdominal aortic aneurysm were significantly older than smokers (mean age: 80.7 (standard deviation: 8.0) vs 68.0 (standard deviation: 11.1), p = 0.003), and age was a significant risk factor only among non-smokers (p = 0.011; p = 0.018 for interaction). Among smokers, the prevalence of abdominal aortic aneurysm was 8.8%, and 72% (n = 18/25) of all diagnosed abdominal aortic aneurysm patients were smokers. Prevalence of undiagnosed abdominal aortic aneurysms among patients with coronary artery disease is high, and history of smoking is the most significant risk factor for abdominal aortic aneurysm. Effectiveness of selective screening of abdominal aortic aneurysm in male patients with coronary artery disease warrants further studies.

2.
Scand J Surg ; 103(4): 226-31, 2014 Dec.
Article in English | MEDLINE | ID: mdl-24737857

ABSTRACT

Surgical wound infection is one of the most common complications after peripheral vascular surgery. It increases the affected patient's risk for major amputation as well as mortality. Furthermore, surgical wound infection is an additional cost. Wound infections after vascular surgery are of multifactorial nature and generally result from the interplay of patient- and procedure-related factors. The use of systemic antibiotic prophylaxis may be the most important method in preventing surgical wound infections. In this review article, we report the current literature of surgical wound infections after peripheral vascular surgery.


Subject(s)
Peripheral Vascular Diseases/surgery , Surgical Wound Infection/etiology , Vascular Surgical Procedures/adverse effects , Antibiotic Prophylaxis/methods , Global Health , Humans , Incidence , Surgical Wound Infection/prevention & control
3.
Eur J Vasc Endovasc Surg ; 47(4): 411-7, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24512892

ABSTRACT

OBJECTIVE: To study the relationship between surgical wound bacterial colonization and the development of surgical site infection (SSI) after lower limb vascular surgery. SSI is a major problem after lower limb vascular surgery. Most SSIs in vascular surgery are caused by Staphylococcal species that are part of normal skin flora. A prospective observational investigator blind study to examine quantitative and qualitative analysis of surgical wound bacterial colonization and the correlation with the development of SSI has been conducted. METHODS: The study cohort comprised 94 consecutive patients with 100 surgical procedures. Swabs for microbiological analyses were taken from surgical wounds at four different time intervals: before surgery, just before the surgical area had been scrubbed, at the end of surgery, and on the first and second postoperative days. Postoperative complications were recorded. RESULTS: Three hundred and eighty-seven skin bacterial samples from 100 surgical wounds were analyzed. The most common bacteria isolated were coagulase-negative staphylococci (80%), Corynebacterium species (25%), and Propionibacterium species (15%). In 13 (62%) cases, the same bacterial isolates were found in the perioperative study samples as in the infected wounds. The incidence of SSI was 21%. Multivariate analysis revealed that high bacterial load on the second postoperative day and diabetes independently increased the risk of SSI. Elective redo surgery was protective against the development of SSI. CONCLUSIONS: A high bacterial load in the postoperative surgical wound independently increases the risk of the development of SSI after lower limb vascular surgery.


Subject(s)
Lower Extremity/surgery , Surgical Wound Infection/epidemiology , Surgical Wound Infection/microbiology , Vascular Surgical Procedures/adverse effects , Aged , Aged, 80 and over , Female , Humans , Incidence , Lower Extremity/microbiology , Male , Middle Aged , Prospective Studies , Risk Factors , Surgical Wound Infection/complications
4.
Scand J Surg ; 99(3): 167-72, 2010.
Article in English | MEDLINE | ID: mdl-21044935

ABSTRACT

BACKGROUND AND AIMS: this multicenter prospective observational study defined the incidence and risk factors of surgical wound infections (SWI) after infrarenal aortic and lower limb vascular surgery procedures and evaluated the severity and costs of these infections. METHODS: the study cohort comprised of 184 consecutive patients. Postoperative complications were recorded. The additional costs attributable to SWI were calculated. RESULTS: Eighty-four (46%) patients had critical ischaemia, 81 (45%) patients underwent infrainguinal bypass surgery and 64 (35%) received vascular prosthesis or prosthetic patch. Forty-nine (27%) patients developed SWI. Staphylococcus aureus was the leading pathogen cultured from the wound. Forty-seven of the 49 infected wounds responded to and healed with the treatment. SWI was the cause of one major amputation. Independent predictors for SWI were infrainguinal surgery (OR 7.2, 95% Cl 2.92-17.65, p < 0.001), obesity (OR 6.1, 95% Cl 2.44-15.16, p < 0.001) and arteriography injection site within the operative area (OR 2.5, 95% Cl 1.13-5.48, p = 0.02). The average cost attributable to SWI was 3320 Ä. CONCLUSION: the incidence of SWI after vascular surgery is high. The risk factors for SWI are infrainguinal surgery, obesity and arteriography injection site within the operative area. SWI increases morbidity and costs of operative treatment.


Subject(s)
Ischemia/surgery , Leg/blood supply , Surgical Wound Infection/economics , Surgical Wound Infection/epidemiology , Vascular Surgical Procedures/adverse effects , Vascular Surgical Procedures/economics , Aged , Aged, 80 and over , Antibiotic Prophylaxis , Aorta, Abdominal/surgery , Aortic Diseases/economics , Aortic Diseases/surgery , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/economics , Comorbidity , Cost of Illness , Female , Finland , Graft Occlusion, Vascular/surgery , Hospital Costs , Hospitalization/economics , Humans , Male , Middle Aged , Obesity/epidemiology , Prospective Studies , Risk Factors , Surgical Wound Infection/prevention & control
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