ABSTRACT
OBJECTIVE: The 10-item Obstetric Quality-of-Recovery 10 scale is a validated patient-reported outcome questionnaire that measures the quality of recovery following delivery. This study aims to develop a Turkish version of the Obstetric Quality of Recovery 10 to evaluate its validity, reliability, and clinical feasibility. METHODS: Term parturients who underwent vaginal delivery or elective caesarean delivery were asked to complete a Turkish version of Obstetric Quality-of-Recovery 10 scoring tool and EuroQol 5-dimension 3L scores (including a global health visual analogue scale) 24 hours after delivery. To validate the Obstetric Quality of Recovery 10-Turkish, we assessed validity, reliability, and clinical feasibility and compared it with the EQ-5D-3L questionnaires. RESULTS: One hundred parturients completed the questionnaire in 24 hours (100% response rate). Obstetric Quality of Recovery 10-Turkish correlated highly with EQ-5D-3L score (r=-0.611) and global health visual analogue scale score (r = 0.652) at 24 hours and discriminated well between good versus poor recovery (global health visual analogue scale score ≥70 vs <70; median interquartile range were 86 [80-90] and 68 [59-75] (P < .001), respectively). Scores were similar for caesarean and vaginal deliveries, 83 (76-89) and 82.5 (69-90), respectively (P = .5). Twenty-four-hour Obstetric Quality of Recovery 10-Turkish scores did not correlate with any baseline demographic and clinical data parameters. Internal consistency was good (Cronbach's alpha=0.87 and inter-item correlation=0.41), and split-half reliability was very good (Spearman-Brown prophesy reliability estimate=0.86). Test-retest reliability was excellent (intra-class correlation coefficient=0.99). No floor or ceiling effects were demonstrated. CONCLUSION: The Obstetric Quality of Recovery 10-Turkish is a valid, reliable, and clinically feasible measure of inpatient postpartum recovery following caesarean and vaginal delivery modes.
ABSTRACT
AIM: Controlled ovarian hyperstimulation results in elevated levels of estrogen during in vitro fertilization (IVF). Although serum ovarian steroid hormones were found to influence central nervous system and anesthetic requirements, the relationship between propofol requirements and serum estrogen concentration in women undergoing oocyte retrieval has not been studied. The aim of this study was to determine the relationship between serum estrogen and progesterone concentrations and the required propofol dose for loss of consciousness (LOC). METHODS: Ninety patients undergoing oocyte retrieval for IVF were enrolled. Anesthesia was induced by administration of 200 mL/h propofol (1%) infusion to reach LOC. Anesthesia was maintained with a propofol infusion guided by entropy. The correlation between estrogen, progesterone levels and propofol dose at the time of LOC was analyzed. Emergence time from anesthesia and total propofol consumption were recorded. RESULTS: The mean serum estradiol concentration was 1825 ±1135 pg/mL. There was a significant positive correlation between serum estradiol and propofol dose required for LOC (Pearson's correlation r = 0.28, P = 0.008). Progesterone had no significant correlation with total propofol dose at the time of LOC. Patients with high estradiol levels (higher than the median value) had similar propofol requirement for LOC, total propofol consumption and emergence time with patients who had low (below the median value) levels. CONCLUSION: Although increased estrogen levels create a positive correlation with propofol dose for LOC, estrogen does not seem to be the only factor for anesthetic requirement of patients undergoing controlled ovarian hyperstimulation.
