1.
Cancer Genet Cytogenet
; 118(1): 62-4, 2000 Apr 01.
Article
in English
| MEDLINE
| ID: mdl-10731593
ABSTRACT
Chronic lymphocytic leukemia (CLL) has been reported to be associated with various chromosomal aberrations, the most common being trisomy 12 and structural rearrangements involving 13q, 11q, and 17p. We present a case of CLL with a constitutional pericentric inversion of chromosome 1.
Subject(s)
Centromere/genetics , Chromosome Inversion , Chromosomes, Human, Pair 1/genetics , Leukemia, Lymphocytic, Chronic, B-Cell/genetics , Chromosome Banding , Humans , Karyotyping , Leukemia, Lymphocytic, Chronic, B-Cell/pathology , Lymphocytes/metabolism , Lymphocytes/pathology , Male , Middle Aged
2.
Cancer Genet Cytogenet
; 106(1): 76-7, 1998 Oct 01.
Article
in English
| MEDLINE
| ID: mdl-9772914
ABSTRACT
A case of acute myelomonocytic leukemia (AMMoL; M4) with a 47,XYY karyotype is reported. This chromosome aneuploidy was found in both bone marrow cells and mitogen-stimulated lymphocytes. The contribution of XYY chromosomal constitution in the pathogenesis of AMMoL is controversial.
