ABSTRACT
Clinical appearance and misdiagnosis in 27 patients having associated preexcitation syndrome and mitral prolapse have been analyzed. Misdiagnosis of myocardial infarction, rheumatic and congenital heart disease, infectious-allergic myocarditis were most typical errors in this condition identification: in 9, 3 and 2 patients, respectively.
Subject(s)
Mitral Valve Prolapse/diagnosis , Wolff-Parkinson-White Syndrome/diagnosis , Adult , Clinical Competence , Diagnostic Errors , Female , Heart Defects, Congenital/diagnosis , Humans , Mitral Valve Prolapse/complications , Myocardial Infarction/diagnosis , Quality of Health Care , Rheumatic Heart Disease/diagnosis , Wolff-Parkinson-White Syndrome/complicationsSubject(s)
Cardiac Complexes, Premature/genetics , Mitral Valve Prolapse/genetics , Tachycardia, Supraventricular/genetics , Adult , Aged , Cardiac Complexes, Premature/complications , Cardiac Complexes, Premature/diagnosis , Female , Humans , Male , Mitral Valve Prolapse/complications , Mitral Valve Prolapse/diagnosis , Pedigree , Syndrome , Tachycardia, Supraventricular/complications , Tachycardia, Supraventricular/diagnosisABSTRACT
Primary prolapse of the mitral valve was diagnosed in 27 (11.7%) out of 230 patients with preexcitation syndrome: 10 of them presented with Wolff-Parkinson-White syndrome, 15 with Clerc-Lévy-Critesco syndrome, and two patients with combination of both syndromes. Preexcitation syndrome combined with mitral valve prolapse manifested itself by different disorders of the cardiac rhythm, mainly by the supraventricular forms: by PST in 17, nonparoxysmal tachycardia in 1, atrial fibrillation paroxysms in 7, sinus tachycardia in 2, supraventricular extrasystole in 3, pacemaker migration in the atria in 1 patient. Clerc-Lévy-Critesco syndrome initiated with atrial fibrillation paroxysms in 7 patients with mitral valve prolapse and with the enlargement of the left atrium. The prognostically unfavourable varieties of the preexcitation syndrome and mitral valve prolapse manifested themselves in ventricular tachycardia progressing to ventricular fibrillation, paroxysmal supraventricular tachycardia with a high frequency of ventricular contractions up to 213-230 and atrial tachyarrhythmia up to 250-280 per minute, which were regarded as factor at risk for potential transformation to ventricular tachycardia; as well as in continuously recurrent attacks of arrhythmia in the presence of multiple AV additional tracts or combined with sinoatrial and atrioventricular block.
