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Ross Fiziol Zh Im I M Sechenova ; 86(4): 422-6, 2000 Apr.
Article in Russian | MEDLINE | ID: mdl-10870217

ABSTRACT

In rats with an incomplete brain ischemia and subsequent reperfusion, the platelets sensitivity to the ADP decreased more obviously during the postischemic reperfusion. The platelets seem to be transformed into a refraction state after their activation in brain ischemia. The platelets refraction state might depend on a secondary activation of the nitric oxide-synthase in the platelets.


Subject(s)
Blood Platelets/physiology , Brain Ischemia/blood , Adenosine Diphosphate/pharmacology , Animals , Arginine/pharmacology , Light , Male , Platelet Aggregation , Rats , Reperfusion , Scattering, Radiation
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