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Genetika ; 25(6): 993-1000, 1989 Jun.
Article in Russian | MEDLINE | ID: mdl-2478418

ABSTRACT

Transcription of the mts271 gene was studied in 27 mouse cell tumor lines. Transcripts of the gene have been found in 6 out of 7 different metastatic lines. No transcription of the gene has been observed in non-metastatic tumor lines. In normal tissues, specific gene DNA was only found in hemopoietic cells--in bone marrow, spleen, thymus and lymphocytes. Transcription of the gene mts271 is not dependent on the level of DNA methylation.


Subject(s)
DNA, Neoplasm/genetics , DNA/genetics , Transcription, Genetic , Animals , Cells, Cultured , Clone Cells , DNA/isolation & purification , DNA, Neoplasm/isolation & purification , Gene Expression , Methylation , Mice , Neoplasm Metastasis , Nucleic Acid Hybridization , RNA/genetics , RNA/isolation & purification , RNA, Neoplasm/genetics , RNA, Neoplasm/isolation & purification , Tumor Cells, Cultured
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