Acinar cell carcinoma of the pancreas: a case report and review of the literature.

The majority of pancreatic malignant tumours are adenocarcinomas of the ductal type, whereas acinar cell carcinoma (ACC) is unusual. Its management is not well codified, resulting from its low frequency. It seems however that curative operative resection represents the best first-line treatment. We present a case of ACC in a 54-year-old woman who presented with right upper quadrant pain of the abdomen due to a pancreatic mass in the head of the pancreas, detected by computer tomography (CT) and magnetic resonance imaging (MRI). In April 2008 the patient underwent a pancreatoduodenectomy (Longmire-Traverso) and received postoperative chemotherapy. We present a case of pancreatic ACC treated with a curative operation followed by chemotherapy. Our patient remains free of the disease and has a good quality of life.

The lymph drainage of the neoplastic mammary glands in the bitch: a lymphographic study.

The purpose of this investigation was to study the lymph drainage of the neoplastic mammary glands in the bitch using indirect lymphography. The main conclusions drawn from the study of 41 natural cases were as follows: the first or cranial thoracic and second or caudal thoracic neoplastic mammary glands usually drain into the ipsilateral axillary lymph nodes and rarely into the ipsilateral axillary and sternal lymph nodes, simultaneously. The third or cranial abdominal neoplastic mammary gland usually drains into the ipsilateral axillary and superficial inguinal lymph nodes simultaneously, but sometimes only cranially into the ipsilateral axillary lymph nodes. Rarely, it drains only caudally into the ipsilateral superficial inguinal and medial iliac lymph nodes, simultaneously. The fourth or caudal abdominal neoplastic mammary gland usually drains only caudally into the ipsilateral superficial inguinal lymph nodes. Rarely, it drains into the ipsilateral axillary and superficial inguinal lymph nodes simultaneously. The fifth or inguinal neoplastic mammary gland usually drains into the ipsilateral superficial inguinal lymph nodes but rarely, does it also drain into the ipsilateral popliteal lymph node and into a lymphatic plexus at the medial aspect of the ipsilateral thigh. Lymphatic connections between the neoplastic and adjacent normal mammary glands were demonstrated in only one case. The lymph drainage pattern of the neoplastic mammary glands is slightly different to that described in normal glands using the same radiographic method.

Absence of cerebrospinal fluid abnormalities and spinal cord lesions after iotrolan cervical myelography in normal cats: an open placebo-controlled study.

Iotrolan (Isovist 300, Schering AG) at a volume of 0.5 ml/kg B.W. was injected into the cerebellomedullary cistern of 12 cats (Isovist group); the same volume of normal saline was injected in four other cats (control group). Two ml of CSF was collected from each anaesthetized cat by cisternal tap immediately before, and 7 and 15 days after, injection. The physical characteristics, specific gravity, total cell count and total protein concentration of each CSF sample were recorded. The cats were euthanized on day 15 immediately after CSF samples and spinal cord specimens had been obtained. Spinal cord histopathology was examined with the aid of light and transmission electron microscopy. The physical characteristics of all the CSF samples were within the reference range. No significant differences were found for CSF specific gravity, total cell count and total protein concentration between the pre-injection samples and those collected 7 and 15 days post-injection in both groups; no spinal cord lesions were detected in histopathology.

Absence of postmyelographic adverse effects and high radiographic resolution of iotrolan used in the cervical myelography for the clinically normal cat: an open-placebo controlled study.

Iotrolan solution at 300 mgI/ml (Isovist 300, Schering AG), was injected into the cerebromedullary cistern in 8 cats (Isovist group), at a volume of 0.5 ml/Kg BW and over one minute. In 3 cats (control group), normal saline was also injected at a same volume and speed. During the subarachnoid injection and at 1, 5 and 10 min thereafter all the cats were being monitored for evidence of respiratory arrest, bradycardia or changes in the arterial blood pressure. The cats were also checked for postmyelographic adverse effects for at least 3 h after their complete recovery from anaesthesia. Postmyelographic neurologic examination was done for 3 consecutive days and the myelographic quality of the films taken at 5 and 15 min postinjection was evaluated. No significant differences were detected between the Isovist and the control groups for all the variables evaluated immediately before, during and up to 3 days after the injection. No actual post-myelographic adverse effects were seen in the animals of both groups. At 15 and 30 min postinjection the opacity, the distention of the subarachnoid space and the detail of all the myelograms obtained were assessed as highly diagnostic.