ABSTRACT
The prevalence of pediatric obesity is increasing and many patients are followed by specialized centers or private doctors. The aim of this study was to verify short- and medium term results of a therapeutic approach based on nutritional intervention in a large pediatric population: 1383 subjects (695 females, 688 males) aged 10.1 +/- 2.7 yr, followed in 11 pediatric departments in Italy. No difference was found between centers in age, height, weight, BMI and IBW. The drop-out rate after the first visit was 30.2% (58.1% IBW > 140%) in females and 34.2% (70.7% IBW > 140%) in males. After two years of follow-up only 9.7% of females and 6.4% of males remained on treatment. Of these patients only 7.3% of females and 6.4% of males had IBW < 120%. These data show that an approach based on nutritional intervention alone is not sufficient for long-term treatment of pediatric obesity. Only an approach started early and involving the family can produce permanent results.
Subject(s)
Obesity/diet therapy , Adolescent , Body Mass Index , Body Weight , Child , Child, Preschool , Diet, Fat-Restricted , Energy Intake , Female , Humans , Italy/epidemiology , Male , Obesity/epidemiology , Patient Compliance , Patient Dropouts , Patient Education as Topic , Treatment FailureABSTRACT
Defects of the middle line are an heterogeneous group of congenital malformations due to commune pathogenetic mechanisms. We have made a case-control study about 150 newborns, who have at least 1 defect of the middle line. Results prove an excess of males between the cases, due mostly to hypospadias. We haven't found families with defects of the middle line with x-linked manner of hereditary transmission. We haven't found any particular risk present in cases and not in controls. We haven't found any case with 2 or more middle line defects.
Subject(s)
Congenital Abnormalities/genetics , Case-Control Studies , Cleft Lip/genetics , Cleft Palate/genetics , Esophageal Atresia/genetics , Esophageal Fistula/genetics , Female , Gestational Age , Humans , Hypospadias/genetics , Infant, Newborn , Male , Sex Factors , Trachea/abnormalitiesSubject(s)
Alleles , Diabetes Mellitus, Type 1/genetics , HLA-DR Antigens/genetics , Child , Female , HLA-DR3 Antigen/genetics , HLA-DR4 Antigen/genetics , Humans , MaleABSTRACT
Authors describe a case of scaphoid megalourethra in a newborn. The child underwent a successful urethroplasty in neonatal period, as described by Nesbitt. In a careful review of the Literature only 47 such cases were found (included the one herein described). Authors discuss etiology, diagnosis and management of this rare malformation and stress the feasibility of an early reconstructive procedure.
