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1.
Nat Rev Cardiol ; 9(8): 464-77, 2012 Apr 24.
Article in English | MEDLINE | ID: mdl-22525668

ABSTRACT

Cardiovascular disease (CVD) is an under-recognized major health problem among women in South-East Asia. The prevalence of cardiovascular risk factors such as hypertension, diabetes mellitus, dyslipidemia, physical inactivity, and being overweight or obese has shown a significantly increasing trend among women in the region, with the exception of Singapore. The problem is compounded by low awareness that CVD is a health problem for women as well as for men, by misconceptions about the disease, and by the lack of suitable, locally available health literature. Efforts have been made by the national heart associations and other organizations to increase heart health awareness and promote healthy lifestyles. Singapore initiated these prevention programs in the early 1990s and has been successful in reducing the prevalence of cardiovascular risk factors. The governments of the region, in accordance with the Noncommunicable Disease Alliance, have begun implementing appropriate preventive strategies and improving health-delivery systems. However, psychological, social, and cultural barriers to cardiovascular health awareness in women need to be addressed before these programs can be fully and successfully implemented.


Subject(s)
Cardiovascular Diseases/epidemiology , Women's Health , Asia, Southeastern/epidemiology , Cardiovascular Diseases/psychology , Diabetes Mellitus/pathology , Dyslipidemias/pathology , Female , Humans , Hypertension/pathology , Obesity/pathology , Perception , Prevalence , Risk Factors , Singapore/epidemiology , Smoking
2.
J Med Assoc Thai ; 85(10): 1113-20, 2002 Oct.
Article in English | MEDLINE | ID: mdl-12501904

ABSTRACT

Prevalence of white-coat hypertension varies approximately 20 per cent among mild hypertensives. When white-coat hypertensives are prescribed antihypertensive medication, there is usually a decrease in clinic blood pressure (BP), but little or no change in 24 hours blood pressure (ABPM). The objective of the study was to test the hypothesis that efficacy of medication therapy for hypertension is identical in any grading of severity of baseline blood pressure. The authors retrospectively analysed ABPM data from mild to moderate hypertensive patients. Efficacy in decreasing blood pressure by antihypertensives has linear relation to baseline blood pressure. Response to antihypertensive agents in white-coat hypertension is minimal but a significant effect still persists and the possibility of hypotensive adverse events from medication in the case cannot be overlooked.


Subject(s)
Amlodipine/therapeutic use , Antihypertensive Agents/therapeutic use , Hypertension/drug therapy , Mibefradil/therapeutic use , Aged , Blood Pressure/drug effects , Blood Pressure/physiology , Female , Humans , Male , Middle Aged , Retrospective Studies , Severity of Illness Index , Treatment Outcome
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