[Congenital vomer agenesis]. / Dogustan vomer yoklugu.

Congenital vomer agenesis is a very rare condition. Usually, it is discovered incidentally. Nasal and otologic diseases accompany the cases. In this article, we report two cases of isolated congenital vomer agenesis who were admitted to our clinic with complaint of nasal obstruction. On endoscopic examination, deviated septum and inferior turbinate hypertrophy were observed in both patients. One patient was performed septoplasty, inferior turbinate radiofrequency, and functional endoscopic sinus surgery. Other patient was advised follow-up since the patient did not consent to operation.

Endoscope-assisted transoral approach to parapharyngeal space tumors.

BACKGROUND: Parapharyngeal space (PPS) tumors are rare tumors for which the surgical management differs widely. The purpose of this study was to discuss the advantages and disadvantages of the endoscope-assisted transoral approach over the traditional approaches. METHODS: This prospective study included 4 patients who were diagnosed with PPS tumors and treated with the endoscope-assisted transoral approach. RESULTS: The endoscope-assisted transoral approach described here safely allowed for the resection of benign neoplasms with high surgical view to the parapharyngeal neurovascular structures. The average tumor size was 42 mm. Three patients had isolated PPS tumors, and 1 patient had a tumor originating from the deep lobe of the parotid gland. The postoperative histopathological diagnosis of the patients was pleomorphic adenoma for 3 of the patients, and marginal zone and follicular hyperplasia for the other. CONCLUSION: This technique provided less operative trauma, a more comfortable postoperative period, and, most importantly, increased operative exposure.

Evaluation of functional results of CWD surgery with ossicular replacement prosthesis due to cholesteatoma using computed tomography.

With the use of high-resolution computed tomography, this retrospective clinical study evaluated the factors affecting hearing in patients who were operated on due to chronic otitis media with cholesteatoma and underwent ossiculoplasty with titanium total ossicular replacement prosthesis (TORP). Fifteen patients with postoperative hearing results of 20 dB or less air-bone gap, and thirteen patients with postoperative hearing results of 21 dB or more air-bone gap were the subjects of this study. All patients were operated on due to chronic otitis media and underwent ossiculoplasty with titanium TORP. High-Resolution Computed Tomography (HRCT) and pure-tone audiometry were performed on each patient after an average of 17 months, postoperatively. Three-dimensional oblique CT cross-sections were analyzed with Vitrea 2(®) software. The presence of soft tissue in the middle ear and contact between the prosthesis head plate and the bone had an adverse effect on hearing (p < 0.05). The angle between the TORP and the oval window did not seem to affect the hearing results (p > 0.05). The study results indicate that an examination of the patients with poor postoperative hearing with HRCT may help find the possible cause and allow for the determination of the prosthesis location.

Relapsing polychondritis and otologic findings.

Relapsing polychondritis is a cartilage tissue disease characterized by inflammatory and destructive episodes. Elastic cartilage of the ear and nose, hyaline cartilage of the joints, hyaline cartilage of vertebra and trachea are the main involvement areas. Also organs having proteoglycan structure such as eyes, heart, blood vessels, and the inner ear can be affected. In this article otologic findings of a 54-year-old male patient with a diagnosis of relapsing polychondritis were presented and discussed in the light of the literature.

Possible protective effect of sertraline against cisplatin-induced ototoxicity: an experimental study.

BACKGROUND/OBJECTIVE: Cisplatin is a widely used chemotherapeutic agent, but its ototoxicity side effect can occur in the majority of patients. Lots of agents were tried to prevent this, but there is not a routine treatment modality yet. The aim of this study was to evaluate the otoprotective effect of sertraline, which is an antidepressant with neuroprotective effects, against cisplatin, in rats. DESIGN: Experimental animal study. MATERIAL AND METHODS: Forty-eight rats were randomly separated in two groups as groups I and II. Group I was identified as the control group and only a single dose of intraperitoneal cisplatin was administered. In group II, in addition to cisplatin, sertraline was administered to the rats through an oral cannula for ten-day period. Distortion product otoacoustic emission measurements were performed at the first day and the 10th day. RESULTS: When the ototoxicity rates after cisplatin in group I and group II in distortion product otoacoustic emission measurements were compared, it was statistically significantly lower in group II in frequencies of 5652, 6165, 6726, 7336, and 7996 Hz (P < 0.05). CONCLUSION: Sertraline seems to have a protective effect on cisplatin ototoxicity and could be used to prevent the ototoxicity and also to treat the depression that occurred in cancer patients together.

Cerebrospinal fluid otorrhea and recurrent bacterial meningitis in a pediatric case with Mondini dysplasia.

Mondini dysplasia is a congenital malformation of the inner ear, which is characterized by a short and large cochlear canal of 1.5 turn rather than 2.5 turns and an apical region with cystic dilatation. Patients present with congenital deafness, when both cochlea are affected. Unilateral disease may cause recurrent meningitis, otorrhea or rhinorrhea. In this article, we report a three-year-old pediatric case with a history of meningitis and cerebrospinal fluid otorrhea following tympanostomy tube placement for serous otitis media.