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Localized intestinal perforations after enteral administration of indomethacin in premature infants.
Alpan, G; Eyal, F; Vinograd, I; Udassin, R; Amir, G; Mogle, P; Glick, B.
J Pediatr ; 106(2): 277-81, 1985 Feb.
Article in English | MEDLINE | ID: mdl-3968618

ABSTRACT

Four very-low-birth-weight infants developed localized intestinal perforations after enteral administration of indomethacin. The clinical picture and histologic findings were unlike those seen in necrotizing enterocolitis.


Subject(s)
Ductus Arteriosus, Patent/drug therapy , Ileal Diseases/chemically induced , Indomethacin/adverse effects , Infant, Low Birth Weight , Intestinal Perforation/chemically induced , Jejunal Diseases/chemically induced , Female , Humans , Ileal Diseases/pathology , Indomethacin/administration & dosage , Infant, Newborn , Intestinal Perforation/pathology , Intubation, Gastrointestinal , Jejunal Diseases/pathology , Male
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