ABSTRACT
Continuous low dose peripheral vein pitressin has been shown to be effective in controlling variceal bleeding in seven episodes of bleeding in six patients. No significant side-effects were seen. The expense, delay and hazard associated with superior mesenteric artery catheterization for selective arterial pitressin infusion were avoided. If these results can be reproduced, low dose peripheral vein pitressin infusion may prove to be a valuable addition to the treatment of bleeding esophageal varices.
Subject(s)
Esophageal and Gastric Varices/drug therapy , Vasopressins/administration & dosage , Adult , Aged , Female , Gastrointestinal Hemorrhage/drug therapy , Humans , Infusions, Parenteral , Male , Middle Aged , Vasopressins/therapeutic useABSTRACT
Transient neutropenia developed in a 62-year-old, white male on maintenance hemodialysis being treated with cimetidine for an in tractable duodenal ulcer. The probable mechanism was peripheral destruction of the granulocyte series, unlike the marrow depression reported with metiamide, another histamine H2 receptor antagonist.
