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Polim Med ; 30(1-2): 45-54, 2000.
Article in Polish | MEDLINE | ID: mdl-11064887

ABSTRACT

Recently, the sol-gel based biomaterials are extendedly investigated in emphasis on theirs medical applications. In this respect it is important to investigate the influence of sol-gel matrices on biological systems. The results of laboratory and biological testing of water extracts of sol-gels are presented in this work. It was proved that it is possible to construct the sol-gels that are not cytotoxic for which the haemolytic reactions fulfils the foreseen norms. This can be achieved by heating the materials in certain temperatures (higher than 350 degrees C). This effect can also be reached by suitably long aging (minimum 6 months).


Subject(s)
Biocompatible Materials , Erythrocytes/drug effects , Materials Testing , Silanes/toxicity , Hemolysis/drug effects , Hot Temperature , Humans , Hydrogen-Ion Concentration , In Vitro Techniques , Silanes/chemistry , Sterilization
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