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1.
Gan To Kagaku Ryoho ; 50(2): 267-269, 2023 Feb.
Article in Japanese | MEDLINE | ID: mdl-36807193

ABSTRACT

INTRODUCTION: There is concerned that prognosis of cancer-bearing patients is adversely affected by postponement of cancer treatment due to infection with a new type of coronavirus(COVID-19). We report a case of thoracic esophageal cancer treated with COVID-19 pneumonia during preoperative CRT. A 60-year-old female diagnosed as having Stage Ⅳ thoracic esophageal cancer(cT3N0M1LYM[104R])started receiving preoperative chemoradiotherapy. On the 12th day, she had a fever and was diagnosed with COVID-19 infection. CRT temporarily interrupted and she was treated for COVID-19 pneumonia preferentially. CRT was resumed promptly after remission. Finally, video-Assisted radical esophagectomy was performed. There were no postoperative complications. Nivolumab was started as an adjuvant therapy on the 2nd postoperative months. CONCLUSIONS: We experienced a case of thoracic esophageal cancer in which COVID-19 pneumonia was treated during preoperative CRT, and CRT and surgery were completed without complications by appropriate treatment.


Subject(s)
COVID-19 , Esophageal Neoplasms , Female , Humans , Middle Aged , Esophageal Neoplasms/surgery , Chemoradiotherapy , Combined Modality Therapy , Prognosis , Esophagectomy , Retrospective Studies , Treatment Outcome , Neoplasm Staging
2.
Gan To Kagaku Ryoho ; 50(13): 1789-1791, 2023 Dec.
Article in Japanese | MEDLINE | ID: mdl-38303208

ABSTRACT

A 50s female was diagnosed as rectal cancer with multiple liver metastases after fecal occult blood scrutiny. Liver metastases were multiple in both lobes and involved the right Glisson's capsule. We determined that the liver metastases were unresectable and initiated FOLFOXIRI plus panitumumab treatment. After 6 courses of chemotherapy, rectal cancer resection was performed. After 12 courses of chemotherapy, the liver metastases which had extensively involved the right Glisson on imaging, shrank until the P7 root was visible. If S7 Glisson could be preserved, the radical resection was planned. If not, associated liver partition and portal vein ligation for staged hepatectomy(ALPPS)was planned. Intraoperatively, it was determined that preservation of S7 Glisson was possible and blood flow preservation in the S7 region was feasible, and an anterior segment hepatic resection(S5-6-8)and lateral segment hepatic partial resection(S2/3)were performed. She was discharged on the 18th day and has been under outpatient observation 12 months after hepatectomy.


Subject(s)
Liver Neoplasms , Rectal Neoplasms , Female , Humans , Hepatectomy/methods , Liver Neoplasms/drug therapy , Liver Neoplasms/surgery , Liver Neoplasms/secondary , Portal Vein/pathology , Rectal Neoplasms/drug therapy , Rectal Neoplasms/surgery , Rectal Neoplasms/pathology , Middle Aged
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