Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Clin Med (Lond) ; 21(1): e71-e76, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33355197

ABSTRACT

Antibiotic stewardship during the COVID-19 pandemic is an important part of a comprehensive strategy to improve patient outcomes and reduce long-term adverse effects secondary to rising antibiotic resistance. This report describes a quality improvement project which incorporates the use of procalcitonin (PCT) testing to rationalise antibiotic prescribing in patients with suspected or confirmed COVID-19 at Chesterfield Royal Hospital. Data were collected from 118 patients with a total of 127 PCT levels checked over a period of 20 days. Each PCT level was correlated with the subsequent antibiotic outcome as well as the result of the COVID-19 PCR swab. Results indicate that antibiotics were either never started or were stopped within 48 hours in 72% of COVID-confirmed cases with a PCT less than 0.25 µg/L. Our findings suggest that procalcitonin testing, when used in combination with thorough clinical assessment, is a safe, simple and sustainable way of reducing antibiotic use in COVID-19.


Subject(s)
Anti-Bacterial Agents/therapeutic use , COVID-19 Drug Treatment , Drug Resistance, Bacterial/drug effects , Hospitals, District , Procalcitonin/therapeutic use , RNA, Viral/analysis , SARS-CoV-2/genetics , COVID-19/epidemiology , COVID-19/virology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pandemics , Retrospective Studies
SELECTION OF CITATIONS
SEARCH DETAIL
...