[Some aspects of current medical treatment of bronchopulmonary suppurations]. / Unele aspecte privind tratamentul medical actual al supuratiilor bronhopulmonare.

Due to their frequency, which is still significant in the frame of respiratory pathology, bronchopulmonary suppurations especially those of the secondary type, developing on previously existing lesions such as chronic bronchitis, bronchiectasis, bronchial asthma, bronchial carcinoma, aerial cysts, etc. rise bacteriological, therapeutical and epidemiologic difficulties for the general practitioner. An analysis is presented, of a group of 619 patients with suppurated bronchopneumopathies, hospitalized in 1980 in a department for lung diseases, of whom 116 had primary, and 503 secondary suppurations. In 177 cases (28.5%) monomorphous flora was identified, from the Ps. aeruginosa and Esch. coli strains, as well as Staphylococcus aureus. In 395 patients (64%) cultures remained sterile, and in 171 cases (27.6%) frequent fungal colonies of the Candida genus were evidenced. The medical treatment, which is sometimes difficult due to the severity and the variety of anatomo-clinical forms of the disease, includes, on an individualized basis, symptomatic therapy, anti-infectious and adjuvant therapy dominated by fluidifying drugs, by antibiotics adapted to the various microbial strains, as well as to particular conditions such as acute episodes or superinfections with anaerobic germs. There is an increased interest for re-establishing immunological balance by substitution medication or bio-stimulating preparations such as mono- or polymicrobial vaccines.

[Still current aspects of primary pulmonary suppurations]. / Aspecte înca actuale in în supuratiile pulmonare primitive.

The paper presents the results of a clinical study carried out in 74 male and 11 female patients presenting with primitive pulmonary suppurations. The onset was of the acute type in 71 cases, and the radiological changes, mainly located in the right lung (in 60 patients) consisted in cavitary aspects -- frequently of the hydro-aerial type in 59 patients, and diffuse non-homogeneous opacities in the other 26. Identification of the germs responsible for the infection in the bronchial secretion maintains its significance, and facilities, with the aid of the antibiogram, an orientation of the therapy. One should stress that the Strep. aureus variety, the pyocyanic bacilli, and Klebsiella strains have determined the most severe forms of the disease. The complex therapy included administration of antibiotics. The treatment was energetic and prolonged. In 63 of the subjects penicillin perfusions were applied, while in 67 of the patients large amounts of antibiotics and sulphonamides were given simultaneously by different routes without iatrogenic effects. The persistence of radiological cavitary sequels in 40 patients (of which in 6 were of important dimensions), and the average duration of the hospitalization (38,4 days, far above the general average for the year 1979 -- 22,2 days), illustrates the difficulties in the assistance of these patients and make necessary practical measures for a rapid diagnosis in view of applying an adequate etiologic therapy, as well as the necessity for dispensarization after discharging, at least for those of the patients that still have cavitary sequelae.

[Post-tuberculosis syndromes in a pneumology unit]. / Sindroamele posttuberculoase într-o sectie de pneumologie.

With reference to 156 patients with a post-tuberculous syndrome, admitted to a pneumology unit, the authors discuss the anatomoclinical aspects of the primary disease and morbid entities developing against the background of the sequelae. The circumstances in which chronic bronchitis develops and post-tuberculous bronchopulmonary suppuration, frequently encountered in the pathology secondary to stable tuberculosis are analyzed. The necessity of preventing potential unspecific diseases and insuring an optimal complex treatment is emphasized.

[Problems concerning the etiopathogenesis of bronchopulmonary suppurations]. / Cu privire la problematica etiopatogeniei supuratiilor bronhopulmonare

The data supplied by analysis of more than 1 000 patients pointed to the wide range of the causal factors, the role of focal infections of the upper respiratory and digestive tracts and the mechanisms that interfere in the determinism of the bronchopulmonary suppurative syndrome, the septic particles migrating as a rule along the bronchogenic route.

[Hyperchronic bronchopulmonary suppurations (clinical study of 100 cases)]. / Supuratii bronhopulmonare hipercronice (Studiu clinic pe 100 cazuri)

Following an analysis of the clinical observations files the authors present a series of aspects and clinical data, as well as functional results in connection with the evolution in out-bursts of 100 cases with bronchopulmonary suppurations dating for more than 10 years. These anatomo-clinical entities, developed either in healthy or on pre-existing lesions, of polymorphous aspect and frequently invalidating, with evident tendencies to relapses, determining considerable difficulties in the application of therapeutical measures, make necessary the dispensarization of patients and this must be organized in the frame of the network for pneumophthysiology, in view of providing the high quality assistance that is necessary in such cases.