ABSTRACT
The effects of exercise (10000 walk steps/day) and diet (1500 kcal/day) for 4 months on coronary risk factors (obesity, hypertension, serum lipid and lipoprotein abnormalities) were studied in 332 obese, middle-aged subjects. Body weight, skinfold thickness, systolic and diastolic blood pressures, serum lipid and lipoproteins (total cholesterol, triglyceride, and beta-lipoprotein) improved significantly (p less than 0.05) during the program. The degree of improvement in blood pressures, serum lipids and lipoproteins was greater in abnormal blood pressure (greater than 140/90 mmHg) or abnormal serum lipid group than in normal group. A significant correlation was observed between daily number of walk steps and the improvement of body weight, diastolic blood pressure and HDL-cholesterol. Increase of daily steps during the program showed a significant (p less than 0.05) correlation to the change in HDL-cholesterol. It was suggested that mild exercise characterized by brisk walking was effective in the treatment of obesity, hypertension and low HDL-cholesterolemia in obese, middle-aged subjects.
Subject(s)
Coronary Disease/prevention & control , Diet, Reducing , Exercise , Obesity , Blood Pressure , Body Weight , Female , Humans , Lipids/blood , Lipoproteins/blood , Male , Middle Aged , Risk Factors , Skinfold Thickness , WalkingABSTRACT
A mini-computer system for PCG interpretation has been functioning since 1971. The system can analyze as many as 100 PCG's in 3 hours. Based on our 5 years' experience, computer interpretation of PCG's has proved itself valuable for the rapid mass-screening of cardiovascular disease. It also provides more objective and quantitative information than human auscultation, though it is still at a developmental stage because of the present technical limitations. The solution of these shortcomings should achieve an automated PCG analysis of high accuracy.
Subject(s)
Cardiovascular Diseases/diagnosis , Diagnosis, Computer-Assisted , Phonocardiography , Computers , Humans , JapanABSTRACT
A 6-year-old boy with coronary artery fistula emptying into the left ventricle was reported. An attempt was made to outline clinical manifestations of this disease which have not yet been fully described, based on the experience of the present case and a review of 14 previously reported cases. It is concluded that clinical signs and symptoms are not specific for this anomaly and retrograde aortography is required to establish the definite diagnosis of the lesion. Authors' views are expounded as to the location of maximal intensity of the murmur, genesis of the systolic murmur and electrocardiographic features.