1.
Lab Anim (NY)
; 32(3): 26-7, 2003 Mar.
Article
in English
| MEDLINE
| ID: mdl-12601386
ABSTRACT
The ISO intracutaneous reactivity test is the standard protocol for determining a medical device's potential for causing irritation. The authors present data indicating that the number of animals required per test can be reduced from three rabbits to two.