ABSTRACT
The functional and metabolic activity of neutrophils, the expression of receptors to the Fc fragment of IgG molecules and C3 of the neutrophilic complement, and the subpopulational affiliation of peripheral lymphocytes were studied to examine immunity in patients with epididymitis. The immunological changes that occur 2-3 days earlier point to the fact that patients with epididymitis and suggest that the methods of immunological testing can be used to predict the course of an inflammatory process and the efficiency of performed treatments.
Subject(s)
Epididymitis/blood , Immunologic Deficiency Syndromes/blood , Neutrophils , T-Lymphocytes , Adolescent , Adult , Epididymitis/complications , Epididymitis/immunology , Humans , Immunologic Deficiency Syndromes/etiology , Immunologic Deficiency Syndromes/immunology , Male , Neutrophils/immunology , T-Lymphocytes/immunologyABSTRACT
Examination of 255 patients with different pyo-inflammatory and septic diseases revealed high effectiveness of the detection of staphylococcal infection by the determination of antigen-binding lymphocytes (ABL) in the indirect rosette-formation test with the use of specially designed staphylococcal erythrocytes immune reagents. ABL were detected in 63% of the examined patients, their content varied between 0.57% and 6.41% (which was, on the average, equal to 1.92 +/- 0.10%). The effectiveness of the method depended on the specificity of the staphylococcal reagent used in the test and on the time of examination of the patients. In patients with acute processes the determination of ABL permitted the diagnosis of staphylococcal infection before the activity of the corresponding serum antibodies could be measured. ABL were classified with T, B and "zero" populations of lymphocytes.
Subject(s)
Antigens, Bacterial/blood , Lymphocytes/immunology , Staphylococcal Infections/diagnosis , Staphylococcus aureus/immunology , Staphylococcus epidermidis/immunology , Acute Disease , Adolescent , Adult , Chronic Disease , Erythrocytes/immunology , Evaluation Studies as Topic , Female , Hemagglutination Tests , Humans , Indicators and Reagents , Male , Middle Aged , Rosette FormationABSTRACT
The authors examined 40 patients with acute puerperal mastitis and 34 healthy puerperas of the control group. Functional activity of the blood microphages and the breast milk macrophages according to the NST-test data has proved to be significantly increased, but at the same time, the decrease in potential possibilities of the cells was noted. Expression of both the types of the blood neutrophile granulocyte receptors increased, and that of the breast milk macrophages decreased.
