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Vestn Dermatol Venerol ; (10): 8-10, 1989.
Article in Russian | MEDLINE | ID: mdl-2609756

ABSTRACT

Experimental findings evidence that the immunity parameters of guinea pigs with 2,4-DNCB-induced allergic contact dermatitis normalize after batriden and dexason therapy, immunosuppressant batriden in low doses alleviating the marked lymphopenic effect of dexason and its inhibitory effect on the peripheral blood neutrophil phagocytic activity. Use of this drug complex will help reduce the hormone dose and thus eliminate the undesirable effects of hormone therapy of allergic diseases of the skin.


Subject(s)
Dermatitis, Contact/drug therapy , Dexamethasone/therapeutic use , Gossypol/analogs & derivatives , Immunosuppressive Agents/therapeutic use , Animals , B-Lymphocytes/drug effects , B-Lymphocytes/immunology , Dermatitis, Contact/immunology , Drug Evaluation, Preclinical , Guinea Pigs , Immunity, Cellular/drug effects , Immunity, Cellular/immunology , T-Lymphocytes/drug effects , T-Lymphocytes/immunology
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